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Literature summary for 3.1.3.86 extracted from

  • Russo, C.M.; Adhikari, A.A.; Wallach, D.R.; Fernandes, S.; Balch, A.N.; Kerr, W.G.; Chisholm, J.D.
    Synthesis and initial evaluation of quinoline-based inhibitors of the SH2-containing inositol 5-phosphatase (SHIP) (2015), Bioorg. Med. Chem. Lett., 25, 5344-5348 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
additional information an amine tethered to the quinoline core is required for SHIP inhibition Homo sapiens
NSC13480 development of stereoselctive synthetic route to inhibitor Homo sapiens
NSC305787 development of stereoselctive synthetic route to inhibitor Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q92835
-
-

Synonyms

Synonyms Comment Organism
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
-
Homo sapiens
SHIP1
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Homo sapiens