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Literature summary for 3.1.3.86 extracted from

  • Kuehbacher, A.; Dambournet, D.; Echard, A.; Cossart, P.; Pizarro-Cerda, J.
    Phosphatidylinositol 5-phosphatase oculocerebrorenal syndrome of Lowe protein (OCRL) controls actin dynamics during early steps of Listeria monocytogenes infection (2012), J. Biol. Chem., 287, 13128-13136.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.3.86

Organism

Organism UniProt Comment Textmining
Danio rerio
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-
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Source Tissue

Source Tissue Comment Organism Textmining
neutrophil
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 Danio rerio
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Synonyms

Synonyms Comment Organism
SH2-domain-containing 5-inositol phosphatase
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 Danio rerio
SHIP
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 Danio rerio

General Information

General Information Comment Organism
malfunction depletion of SHIP 5'-phosphatases increases neutrophil wound attraction and random motility through a PI3K-dependent pathway. Ectopic expression of the SHIP1 phosphatase domain impairs neutrophil migration Danio rerio
physiological function SHIP phosphatases serve as a brake that limit neutrophil motility and inflammation, at least in part through their effects on PI3K signaling Danio rerio