Cloned (Comment) | Organism |
---|---|
overexpressed as His-tagged fusion protein | Escherichia coli |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
24900 | - |
x * 24900, SDS-PAGE | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glycero-D-manno-heptose 1,7-bisphosphate + H2O | Escherichia coli | synthesis of ADP-D-beta-D-heptose in Escherichia coli requires three proteins, GmhA (sedoheptulose 7-phosphate isomerase), HldE (bifunctional D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase), and GmhB (D,D-heptose 1,7-bisphosphate phosphatase) | D-glycero-D-manno-heptose 1-phosphate + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P63228 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glycero-D-manno-heptose 1,7-bisphosphate + H2O | - |
Escherichia coli | D-glycero-D-manno-heptose 1-phosphate + phosphate | - |
? | |
D-glycero-D-manno-heptose 1,7-bisphosphate + H2O | synthesis of ADP-D-beta-D-heptose in Escherichia coli requires three proteins, GmhA (sedoheptulose 7-phosphate isomerase), HldE (bifunctional D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase), and GmhB (D,D-heptose 1,7-bisphosphate phosphatase) | Escherichia coli | D-glycero-D-manno-heptose 1-phosphate + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 24900, SDS-PAGE | Escherichia coli |
General Information | Comment | Organism |
---|---|---|
malfunction | deletion of gmhB causes a partial defect in the synthesis of the lipopolysaccharide core, resulting in the formation of heptoseless and heptose-rich forms | Escherichia coli |