Literature summary for 3.1.3.75 extracted from

Stewart, A.J.; Roberts, S.J.; Seawright, E.; Davey, M.G.; Fleming, R.H.; Farquharson, C.
The presence of PHOSPHO1 in matrix vesicles and its developmental expression prior to skeletal mineralization (2006), Bone, 39, 1000-1007.

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Activating Compound

Activating Compound	Comment	Organism	Structure
ascorbic acid	increases PHOSPHO1 expression in matrix vesicles after 12 days in culture	Gallus gallus

Application

Application	Comment	Organism
medicine	role in the early stages of matrix mineralization	Gallus gallus

Organism

Organism	UniProt	Comment	Textmining
Gallus gallus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
adult	mineralization by PHOSPHO1 in medullary bone	Gallus gallus	-
bone	high levels in matrix vesicles from growth plate chondrocytes	Gallus gallus	-
embryo	PHOSPHO1 expression occurs prior to E6.5 and is initially restricted to the bone collar within the mid-shaft of the diaphysis of long bones. By E11.5, expression is observed over the entire length of the diaphysis	Gallus gallus	-

Synonyms

Synonyms	Comment	Organism
PHOSPHO1	-	Gallus gallus

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Release 2023.1 (January 2023)