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Literature summary for 3.1.3.74 extracted from

  • Hwang, I.K.; Yoo, K.Y.; Kim, d.o.H.; Lee, B.H.; Kwon, Y.G.; Won, M.H.
    Time course of changes in pyridoxal 5-phosphate (vitamin B6 active form) and its neuroprotection in experimental ischemic damage (2007), Exp. Neurol., 206, 114-125.
    View publication on PubMed
Search for more literature for 3.1.3.74

Organism

Organism UniProt Comment Textmining
Meriones unguiculatus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
astrocyte 4-5 days after ischemia PLP-P expressed in glial components Meriones unguiculatus
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brain
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 Meriones unguiculatus
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hippocampus after 3 h after ischemia/reperfusion, PLP-P decreases significantly in the CA1 region. 12 h after ischemia PLP-P in the CA1 region slightly increases, thereafter time-dependent increase. PLP-P protein level highest 2 days after ischemia, whereas 4 days after ischemia PLP-P decreases/disappears Meriones unguiculatus
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neuron
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 Meriones unguiculatus
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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 total activity of PLP-P significantly increases 2 days after ischemia, whereas the specific activity is not altered Meriones unguiculatus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pyridoxal 5'-phosphate + H2O
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 Meriones unguiculatus pyridoxal + phosphate
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 ?

Synonyms

Synonyms Comment Organism
PLP phosphatase
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 Meriones unguiculatus
PLP-P
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 Meriones unguiculatus
pyridoxal phosphate phosphatase
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 Meriones unguiculatus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
-
 Meriones unguiculatus