Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.3.56 extracted from

  • Erneux, C.; Govaerts, C.; Communi, D.; Pesesse, X.
    The diversity and possible functions of the inositol polyphosphate 5-phosphatases (1998), Biochim. Biophys. Acta, 1436, 185-199.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2,3-bisphosphoglycerate
-
Homo sapiens
N-ethylmaleimide
-
Homo sapiens
Phenylglyoxal Arg-343 and Arg-350 were found to be covalently modified; irreversible, substrates and 2,3-bisphosphoglycerate protect against inactivation Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane membrane associated enzyme has lower specific activity than soluble enzyme Homo sapiens 16020
-
soluble
-
Homo sapiens
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O Homo sapiens
-
D-myo-inositol 1,3,4-trisphosphate + phosphate
-
?
D-myo-inositol 1,4,5-trisphosphate + H2O Homo sapiens regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate D-myo-inositol 1,4-bisphosphate + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
side-chain modification isoprenylation Homo sapiens
side-chain modification farnesylation Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O
-
Homo sapiens D-myo-inositol 1,3,4-trisphosphate + phosphate
-
?
D-myo-inositol 1,4,5-trisphosphate + H2O
-
Homo sapiens D-myo-inositol 1,4-bisphosphate + phosphate
-
?
D-myo-inositol 1,4,5-trisphosphate + H2O regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate Homo sapiens D-myo-inositol 1,4-bisphosphate + phosphate
-
?