Literature summary for 3.1.3.53 extracted from

Qiao, Y.N.; He, W.Q.; Chen, C.P.; Zhang, C.H.; Zhao, W.; Wang, P.; Zhang, L.; Wu, Y.Z.; Yang, X.; Peng, Y.J.; Gao, J.M.; Kamm, K.E.; Stull, J.T.; Zhu, M.S.
Myosin phosphatase target subunit 1 (MYPT1) regulates the contraction and relaxation of vascular smooth muscle and maintains blood pressure (2014), J. Biol. Chem., 289, 22512-22523.

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Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q9DBR7	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
vascular smooth muscle cell	-	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
myosin phosphatase target subunit 1	-	Mus musculus
MYPT1	-	Mus musculus

General Information

General Information	Comment	Organism
malfunction	deletion of MYPT1 in vascular smooth muscle enhances RLC (myosin regulatory light chain) phosphorylation and contractile activity, which may contribute to the development of hypertension in vivo	Mus musculus

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Release 2023.1 (January 2023)