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Literature summary for 3.1.3.53 extracted from

  • Azam, M.A.; Yoshioka, K.; Ohkura, S.; Takuwa, N.; Sugimoto, N.; Sato, K.; Takuwa, Y.
    Ca2+-independent, inhibitory effects of cyclic adenosine 5-monophosphate on Ca2+ regulation of phosphoinositide 3-kinase C2alpha, Rho, and myosin phosphatase in vascular smooth muscle (2007), J. Pharmacol. Exp. Ther., 320, 907-916.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
KCl in organ culture Oryctolagus cuniculus

Inhibitors

Inhibitors Comment Organism Structure
additional information forskolin, the phosphoinositide 3-kinase inhibitor 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one, LY 294002, and the Rho kinase inhibitor (R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide, Y27632, inhibit KCl-induced contraction in organ culture Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
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Japanese male white
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Source Tissue

Source Tissue Comment Organism Textmining
aortic smooth muscle
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Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
myosin light-chain phosphate + H2O muscle Oryctolagus cuniculus myosin light-chain + phosphate
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?

Synonyms

Synonyms Comment Organism
MLCP
-
Oryctolagus cuniculus
myosin light chain phosphatase
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Oryctolagus cuniculus
myosin phosphatase
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Oryctolagus cuniculus
myosin-targeting protein 1
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Oryctolagus cuniculus
MYPT1
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Oryctolagus cuniculus