Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | C-terminal leucine-zipper of MYPT 1 subunit is required for cGMP-mediated activation of enzyme | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
isoforms of enzyme targeting subunit 1, MYPT 1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | portal vein, expression of MYPT 1 subunit increases 2fold between postnatal days 6 and 12 with similar increase in enzyme activity. MYPT 1 switches from leucine-zipper positive to leucine-zipper negative isoforms, concordant with a switch from sensitive to resisitant to cGMP-mediated vascular relaxation | Rattus norvegicus | - |