Literature summary for 3.1.3.5 extracted from

Meurillon, M.; Marton, Z.; Hospital, A.; Jordheim, L.P.; Bejaud, J.; Lionne, C.; Dumontet, C.; Perigaud, C.; Chaloin, L.; Peyrottes, S.
Structure-activity relationships of beta-hydroxyphosphonate nucleoside analogues as cytosolic 5-nucleotidase II potential inhibitors: synthesis, in vitro evaluation and molecular modeling studies (2014), Eur. J. Med. Chem., 77, 18-37.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
molecular modeling study using inhibitor 1-(6-deoxy-6-phosphono-beta-D-allofuranosyl)-5-(2-(E)-phenylvinyl)-cytosine	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
1-(6-deoxy-6-phosphono-beta-D-allofuranosyl)-5-(2-(E)-phenylvinyl)-cytosine	-	Homo sapiens
1-(6-deoxy-6-phosphono-beta-D-allofuranosyl)-5-phenyl-cytosine	-	Homo sapiens
1-(6-deoxy-6-phosphono-beta-D-allofuranosyl)-cytosine	-	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Homo sapiens	5829	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P49902	-	-

Synonyms

Synonyms	Comment	Organism
cN-II	-	Homo sapiens

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
1.14	-	1-(6-deoxy-6-phosphono-beta-D-allofuranosyl)-5-(2-(E)-phenylvinyl)-cytosine	pH 6.5, 37°C	Homo sapiens
1.74	-	1-(6-deoxy-6-phosphono-beta-D-allofuranosyl)-cytosine	pH 6.5, 37°C	Homo sapiens
2.01	-	1-(6-deoxy-6-phosphono-beta-D-allofuranosyl)-5-phenyl-cytosine	pH 6.5, 37°C	Homo sapiens

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Release 2023.1 (January 2023)