Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.3.5 extracted from

  • Russo-Abrahao, T.; Cosentino-Gomes, D.; Daflon-Yunes, N.; Meyer-Fernandes, J.R.
    Giardia duodenalis: biochemical characterization of an ecto-5'-nucleotidase activity (2011), Exp. Parasitol., 127, 66-71.
    View publication on PubMed
Search for more literature for 3.1.3.5

Inhibitors

Inhibitors Comment Organism Structure
Ammonium molybdate
-
 Giardia intestinalis

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface
-
 Giardia intestinalis 9986
-
membrane
-
 Giardia intestinalis 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
additional information no effect on the enzyme activity by divalent cations or NaF Giardia intestinalis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5'-AMP + H2O Giardia intestinalis
-
 adenosine + phosphate
-
 ?
5'-CMP + H2O Giardia intestinalis
-
 cytidine + phosphate
-
 ?
5'-GMP + H2O Giardia intestinalis
-
 guanosine + phosphate
-
 ?
5'-IMP + H2O Giardia intestinalis
-
 inosine + phosphate
-
 ?
5'-UMP + H2O Giardia intestinalis
-
 uridine + phosphate
-
 ?
additional information Giardia intestinalis 5'-nucleotidase catalyzes the hydrolysis of the phosphoric ester bond of nucleoside 5'-monophosphates, such as AMP, CMP, UMP, IMP and GMP, to the corresponding nucleosides and phosphate ?
-
 ?

Organism

Organism UniProt Comment Textmining
Giardia intestinalis
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
trophozoite
-
 Giardia intestinalis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-AMP + H2O
-
 Giardia intestinalis adenosine + phosphate
-
 ?
5'-AMP + H2O best substrate Giardia intestinalis adenosine + phosphate
-
 ?
5'-CMP + H2O
-
 Giardia intestinalis cytidine + phosphate
-
 ?
5'-GMP + H2O
-
 Giardia intestinalis guanosine + phosphate
-
 ?
5'-IMP + H2O
-
 Giardia intestinalis inosine + phosphate
-
 ?
5'-UMP + H2O
-
 Giardia intestinalis uridine + phosphate
-
 ?
additional information 5'-nucleotidase catalyzes the hydrolysis of the phosphoric ester bond of nucleoside 5'-monophosphates, such as AMP, CMP, UMP, IMP and GMP, to the corresponding nucleosides and phosphate Giardia intestinalis ?
-
 ?

Synonyms

Synonyms Comment Organism
ecto-5'-nucleotidase
-
 Giardia intestinalis
More the enzyme belongs to the the 5'-nucleotidase family Giardia intestinalis

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Giardia intestinalis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
 assay at Giardia intestinalis