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Literature summary for 3.1.3.5 extracted from

  • Careddu, M.G.; Allegrini, S.; Pesi, R.; Camici, M.; Garcia-Gil, M.; Tozzi, M.G.
    Knockdown of cytosolic 5'-nucleotidase II (cN-II) reveals that its activity is essential for survival in astrocytoma cells (2008), Biochim. Biophys. Acta, 1783, 1529-1535.
    View publication on PubMed
Search for more literature for 3.1.3.5

Application

Application Comment Organism
medicine the activation of apoptosis caused by the knockdown of cN-II opens a new possibility for developing strategies aimed at overcoming tumour invasiveness and resistance to chemotherapy Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
ADF cell
-
 Homo sapiens
-
astrocytoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-AMP + H2O
-
 Homo sapiens adenosine + phosphate
-
 ?
5'-GMP + H2O
-
 Homo sapiens guanosine + phosphate
-
 ?
5'-IMP + H2O preferred substrate Homo sapiens inosine + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
cN-II
-
 Homo sapiens
cytosolic 5'-nucleotidase II
-
 Homo sapiens