KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.41 | - |
5'-inosinic acid | 37°C, pH 7.5 | Salvator rufescens | |
0.58 | - |
5'-inosinic acid | 37°C, pH 7.5 | Varanus gouldii | |
0.83 | - |
5'-inosinic acid | 37°C, pH 7.5 | Crocodylus siamensis | |
7.1 | - |
5'-AMP | 37°C, pH 7.5 | Salvator rufescens | |
7.3 | - |
5'-AMP | 37°C, pH 7.5 | Varanus gouldii | |
13.6 | - |
5'-AMP | 37°C, pH 7.5 | Crocodylus siamensis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Varanus gouldii | high enzyme activity in liver is a feature of constitutive uricotelism, enzyme may participate in the production of uric acid | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Crocodylus siamensis | - |
- |
- |
Salvator rufescens | - |
- |
- |
Varanus gouldii | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Salvator rufescens | - |
liver | - |
Crocodylus siamensis | - |
liver | - |
Varanus gouldii | - |
additional information | high enzyme activity in decreasing order: kidney, liver, testis, spleen | Salvator rufescens | - |
additional information | high enzyme activity in decreasing order: liver, kidney, spleen | Crocodylus siamensis | - |
additional information | high enzyme activity in decreasing order: liver, kidney, spleen | Varanus gouldii | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-glycerophosphate + H2O | 1% of the activity with 5-IMP | Varanus gouldii | glycerol + phosphate | - |
? | |
5'-AMP + H2O | 17% of the activity with 5-IMP | Crocodylus siamensis | adenosine + phosphate | - |
? | |
5'-AMP + H2O | 30% of the activity with 5-IMP | Salvator rufescens | adenosine + phosphate | - |
? | |
5'-AMP + H2O | 32% of the activity with 5-IMP | Varanus gouldii | adenosine + phosphate | - |
? | |
5'-CMP + H2O | 11% of the activity with 5-IMP | Varanus gouldii | cytidine + phosphate | - |
? | |
5'-CMP + H2O | 17% of the activity with 5-IMP | Salvator rufescens | cytidine + phosphate | - |
? | |
5'-CMP + H2O | 21% of the activity with 5-IMP | Crocodylus siamensis | cytidine + phosphate | - |
? | |
5'-dIMP + H2O | - |
Crocodylus siamensis | deoxyinosine + phosphate | - |
? | |
5'-dIMP + H2O | 102% of the activity with 5-IMP | Crocodylus siamensis | deoxyinosine + phosphate | - |
? | |
5'-dIMP + H2O | 95% of the activity with 5-IMP | Salvator rufescens | deoxyinosine + phosphate | - |
? | |
5'-dIMP + H2O | 99% of the activity with 5-IMP | Varanus gouldii | deoxyinosine + phosphate | - |
? | |
5'-dTMP + H2O | 10% of the activity with 5-IMP | Varanus gouldii | deoxythymidine + phosphate | - |
? | |
5'-dTMP + H2O | 17.5% of the activity with 5-IMP | Salvator rufescens | deoxythymidine + phosphate | - |
? | |
5'-dTMP + H2O | 7.1% of the activity with 5-IMP | Crocodylus siamensis | deoxythymidine + phosphate | - |
? | |
5'-GMP + H2O | 104% of the activity with 5-IMP | Varanus gouldii | guanosine + phosphate | - |
? | |
5'-GMP + H2O | 89% of the activity with 5-IMP | Crocodylus siamensis | guanosine + phosphate | - |
? | |
5'-GMP + H2O | 99% of the activity with 5-IMP | Salvator rufescens | guanosine + phosphate | - |
? | |
5'-IMP + H2O | - |
Varanus gouldii | inosine + phosphate | - |
? | |
5'-IMP + H2O | - |
Salvator rufescens | inosine + phosphate | - |
? | |
5'-IMP + H2O | 8% of the activity with 5-IMP | Varanus gouldii | inosine + phosphate | - |
? | |
5'-inosinic acid + H2O | - |
Crocodylus siamensis | ? | - |
? | |
5'-UMP + H2O | 33% of the activity with 5-IMP | Varanus gouldii | uridine + phosphate | - |
? | |
5'-UMP + H2O | 41% of the activity with 5-IMP | Crocodylus siamensis | uridine + phosphate | - |
? | |
5'-UMP + H2O | 56% of the activity with 5-IMP | Salvator rufescens | uridine + phosphate | - |
? | |
additional information | high enzyme activity in liver is a feature of constitutive uricotelism, enzyme may participate in the production of uric acid | Varanus gouldii | ? | - |
? | |
additional information | no substrate: 3'-IMP, 1-glycerophosphate | Crocodylus siamensis | ? | - |
? | |
additional information | no substrate: 3'-IMP, 1-glycerophosphate | Salvator rufescens | ? | - |
? |