Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.3.5 extracted from

  • Liu, X.W.; Sok, D.E.
    Oxidative inactivation of brain ecto-5'-nucleotidase by thiols/Fe2+ system (2000), Neurochem. Res., 25, 1475-1484.
    View publication on PubMed
Search for more literature for 3.1.3.5

Inhibitors

Inhibitors Comment Organism Structure
2-mercaptoethanol
-
 Bos taurus
Cys-Gly
-
 Bos taurus
cysteamine
-
 Bos taurus
dithiothreitol
-
 Bos taurus
Fe2+ oxidative inactivation in a Fe2+/GSH system may be related to the selective association of Fe2+ and thiols to the enzyme molecule Bos taurus
gamma-glutamylcysteine
-
 Bos taurus
GSH
-
 Bos taurus
L-cysteine
-
 Bos taurus
L-cysteine ethyl ester
-
 Bos taurus
N-acetylcysteine
-
 Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Bos taurus 16020
-

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Bos taurus
-

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.009
-
 L-cysteine ethyl ester pH 7.4, 38°C Bos taurus
0.041
-
 Cys-Gly pH 7.4, 38°C Bos taurus
0.09
-
 dithiothreitol pH 7.4, 38°C Bos taurus
0.32
-
 L-cysteine pH 7.4, 38°C Bos taurus
2.4
-
 cysteamine pH 7.4, 38°C Bos taurus
3.2
-
 N-acetylcysteine pH 7.4, 38°C Bos taurus
3.6
-
 GSH pH 7.4, 38°C Bos taurus
3.7
-
 gamma-glutamylcysteine pH 7.4, 38°C Bos taurus
13
-
 2-mercaptoethanol pH 7.4, 38°C Bos taurus