Literature summary for 3.1.3.5 extracted from

Allegrini, S.; Scaloni, A.; Ferrara, L.; Pesi, R.; Pinna, P.; Sgarrella, F.; Camici, M.; Eriksson, S.; Tozzi, M.G.
Bovine cytosolic 5'-nucleotidase acts through the formation of an aspartate 52-phosphoenzyme intermediate (2001), J. Biol. Chem., 276, 33526-33532.

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Protein Variants

Protein Variants	Comment	Organism
42DELTAN	inactive mutant enzyme	Bos taurus
D52A	inactive mutant enzyme	Bos taurus
D52E	inactive mutant enzyme	Bos taurus
D54A	inactive mutant enzyme	Bos taurus
D54E	inactive mutant enzyme	Bos taurus

Inhibitors

Inhibitors	Comment	Organism	Structure
Woodward's reagent K	-	Bos taurus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Bos taurus	5829	-

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	the enzyme acts through the formation of a phosphoenzyme intermediate, essential role of Asp52 in the catalytic machinery, Asp54 assists in the formation of the acyl phosphate species	Bos taurus	?	-	?

Synonyms

Synonyms	Comment	Organism
cN-II	-	Bos taurus
cytosolic 5'-nucleotidase/phosphotransferase	-	Bos taurus

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Release 2023.1 (January 2023)