Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ADP | activates cNI and cNII | Homo sapiens | |
ATP | activates cNII, no effect on cNI | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | inhibits eNs | Homo sapiens | |
ATP | inhibits eNs, no effect on cNI | Homo sapiens | |
phosphate | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | cytosolic nucleotidases: cNI, cNII and eNs | Homo sapiens | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | activates cNI, cNII and eNs | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | patients with nucleotidase-associated pervasive developmental disorder exhibit altered electrophoretic mobility of cytosolic 5'-nucleotidase | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-AMP + H2O | preferred substrate for cNI and eNs | Homo sapiens | adenosine + phosphate | - |
? | |
5'-IMP + H2O | preferred substrate for cNII | Homo sapiens | inosine + phosphate | - |
? | |
additional information | patients with nucleotidase-associated pervasive developmental disorder exhibit altered electrophoretic mobility of cytosolic 5'-nucleotidase | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cNI | - |
Homo sapiens |
cNII | - |
Homo sapiens |
eNs | - |
Homo sapiens |