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Literature summary for 3.1.3.48 extracted from

  • Buzalaf, M.A.R.; Taga, E.M.; Granjeiro, J.M.; Ferreira, C.V.; Lourencao, V.A.; Ortega, M.M.; Poletto, D.W.; Aoyama, H.
    Kinetic characterization of bovine lung low-molecular-weight protein tyrosine phosphatase (1998), Exp. Lung Res., 24, 269-272.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Cu2+ lung enzyme Bos taurus
Fe2+ lung enzyme Bos taurus
L-Tartrate no inhibition of lung enzyme Bos taurus
NaF no inhibition of lung enzyme Bos taurus
p-chloromercuribenzoate lung enzyme Bos taurus
Zn2+
-
Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
FMN + H2O Bos taurus lung enzyme ?
-
?
phosphotyrosine + H2O Bos taurus lung enzyme tyrosine + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
47
-
-
Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-naphthyl phosphate + H2O 89.3% of the activity with 4-nitrophenyl phosphate, lung enzyme Bos taurus 1-naphthol + phosphate
-
?
4-nitrophenyl phosphate + H2O
-
Bos taurus 4-nitrophenol + phosphate
-
?
FMN + H2O 71.8% of the activity with 4-nitrophenyl phosphate, lung enzyme Bos taurus ? + phosphate
-
?
FMN + H2O lung enzyme Bos taurus ?
-
?
phosphotyrosine + H2O 45.2% of the activity with 4-nitrophenyl phosphate, lung enzyme Bos taurus tyrosine + phosphate
-
?
phosphotyrosine + H2O lung enzyme Bos taurus tyrosine + phosphate
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
-
Bos taurus