Cloned (Comment) | Organism |
---|---|
gene Bmptp-h, functional recombinant overexpression of N-terminally FLAG-tagged enzyme in Bombyx mori larvae, transfection via dsRNA injection into larvae or viral infection method, quantitative real-time PCR expression analysis and expression profile of Bmptp-h during the development and in different tissues, overview. Recombinant expression of Flag-tagged BmPTP-h in BmE cells via viral transfection, overexpression of Bmptp-h enhances Bombyx mori nucleopolyhedrovirus (BmNPV) replication in BmE cells | Bombyx mori |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bombyx mori | Q75T82 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
Bmptp-h | - |
Bombyx mori |
protein tyrosine phosphatase | - |
Bombyx mori |
PTP | - |
Bombyx mori |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Bombyx mori |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Bombyx mori |
General Information | Comment | Organism |
---|---|---|
evolution | among the 36 PTP genes, gene ptp-h, which is proposed to be the origin of baculovirus ptp, belongs to atypical VH1-like dual-specific PTP subset and encodes a catalytic active protein. PTP variants and subfamilies in Bombyx mori, overview | Bombyx mori |
physiological function | recombinant overexpression of enzyme Bmptp-h enhances BmNPV replication in BmE cells. Enzyme BmPTP-h acts as a host factor facilitating baculovirus infection via promoting its DNA replication, the enzyme is involved in the host-virus interactions that control the viral replication | Bombyx mori |