Cloned (Comment) | Organism |
---|---|
expressed in Saccharomyces cerevisiae YPH499 cells | Mus musculus |
expressed in Saccharomyces cerevisiae YPH499 cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
C215S | phosphatase-dead mutant of PTP1B | Homo sapiens |
C216S | phosphatase-dead mutant of TCPTP | Homo sapiens |
C231S | phosphatase-dead mutant of PEST | Homo sapiens |
C433S | phosphatase-dead mutant of PTPalpha | Homo sapiens |
C459S | phosphatase-dead mutant of Shp2 | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
[a protein]-tyrosine phosphate + H2O | Mus musculus | - |
[a protein]-tyrosine + phosphate | - |
? | |
[a protein]-tyrosine phosphate + H2O | Homo sapiens | - |
[a protein]-tyrosine + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[a protein]-tyrosine phosphate + H2O | - |
Mus musculus | [a protein]-tyrosine + phosphate | - |
? | |
[a protein]-tyrosine phosphate + H2O | - |
Homo sapiens | [a protein]-tyrosine + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PEST | - |
Homo sapiens |
protein tyrosine phosphatase | - |
Mus musculus |
protein tyrosine phosphatase | - |
Homo sapiens |
PTP | - |
Mus musculus |
PTP | - |
Homo sapiens |
PTPalpha | - |
Homo sapiens |
SHP2 | - |
Mus musculus |
T-cell protein tyrosine phosphatase | - |
Homo sapiens |
TCPTP | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is capable of rescuing the effects of v-Src toxicity | Mus musculus |
physiological function | the enzyme is capable of rescuing the effects of v-Src toxicity | Homo sapiens |