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Literature summary for 3.1.3.48 extracted from

  • Mukhopadhyay, A.; Kennelly, P.J.
    A low molecular weight protein tyrosine phosphatase from c: enzymatic characterization and identification of its potential substrates (2011), J. Biochem., 149, 551-562.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
Ammonium molybdate strong inhibition Synechocystis sp.
sodium orthovanadate strong inhibition Synechocystis sp.
Zn2+ strong inhibition Synechocystis sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Synechocystis sp. SynPTP displays catalytic activity towards all tyrosyl-phosphorylated proteins, but fails to dephosphorylate the same serylphosphorylated substrates, SynPTP functions as a protein tyrosine phosphatase not as a dual-specific phosphatase ?
-
?

Organism

Organism UniProt Comment Textmining
Synechocystis sp.
-
ORF slr0328
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
casein tyrosine phosphate + H2O
-
Synechocystis sp. casein tyrosine + phosphate
-
?
additional information SynPTP displays catalytic activity towards all tyrosyl-phosphorylated proteins, but fails to dephosphorylate the same serylphosphorylated substrates, SynPTP functions as a protein tyrosine phosphatase not as a dual-specific phosphatase Synechocystis sp. ?
-
?
additional information the enzyme is also active on 4-nitrophenyl phosphate Synechocystis sp. ?
-
?

Synonyms

Synonyms Comment Organism
low molecular weight protein tyrosine phosphatase
-
Synechocystis sp.
protein tyrosine phosphatase
-
Synechocystis sp.
SynPTP
-
Synechocystis sp.

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
assay at Synechocystis sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
assay at Synechocystis sp.