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BRENDA support

Literature summary for 3.1.3.48 extracted from

  • Easton, J.B.; Royer, A.R.; Middlemas, D.S.
    The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by brain-derived neurotrophic factor (2006), J. Neurochem., 97, 834-845.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus enzyme isoform Shp2 is required for complete activation of mitogen-activated protein kinases MAPKs by brain-derived neurotropic factor ?
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?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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isoform Shp2
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Source Tissue

Source Tissue Comment Organism Textmining
NB-1643 cell neuroblastoma cell Rattus norvegicus
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Rat2 cell
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Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme isoform Shp2 is required for complete activation of mitogen-activated protein kinases MAPKs by brain-derived neurotropic factor Rattus norvegicus ?
-
?