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Literature summary for 3.1.3.47 extracted from

  • Gil G.; Hegardt F.
    Some properties of purified 3-hydroxy-3-methylglutaryl Coenzyme A reductase phosphatase from rat liver (1982), Arch. Biochem. Biophys., 214, 192-198.
    View publication on PubMed
Search for more literature for 3.1.3.47

Inhibitors

Inhibitors Comment Organism Structure
citrate
-
 Rattus norvegicus
CoA
-
 Rattus norvegicus
EDTA does not inhibit all reductase phosphatase isoenzymes Rattus norvegicus
fluoride
-
 Rattus norvegicus
hydroxymethylglutaryl-CoA does not inhibit the reductase phosphatase itself but interacts with the reductase and prevents its activation Rattus norvegicus
NADPH does not inhibit the reductase phosphatase itself but interacts with the reductase and prevents its activation Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-
microsome
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O Rattus norvegicus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
liver Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
fetus
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O
-
 Rattus norvegicus [hydroxymethylglutaryl-CoA reductase (NADPH)] + phosphate
-
 ?
[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O
-
 Rattus norvegicus ?
-
 ?