Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.3.44 extracted from

  • Krakower, G.R.; Kim, K.H.
    Purification and properties of acetyl-CoA carboxylase phosphatase (1981), J. Biol. Chem., 256, 2408-2413.
    View publication on PubMed
Search for more literature for 3.1.3.44

Inhibitors

Inhibitors Comment Organism Structure
acetyl-CoA carboxylase inhibits dephosphorylation of phosphoprotamine Rattus norvegicus
F- 50 mM, no effect on dephosphorylation of [acetyl-CoA carboxylase], strong inhibition of the dephosphorylation of [phosphorylase a]-phosphate Rattus norvegicus
phosphate strong inhibitor when phosphoprotamine or [phosphorylase a]-phosphate is the substrate, the effect is far less apparent when [acetyl-CoA carboxylase]-phosphate is used as the substrate Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0015
-
 [acetyl-CoA carboxylase]-phosphate
-
 Rattus norvegicus
0.037
-
 [glycogen phosphorylase A]-phosphate
-
 Rattus norvegicus
0.076
-
 phosphoprotamine
-
 Rattus norvegicus
1.34
-
 p-nitrophenyl phosphate
-
 Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
71000
-
 gel filtration Rattus norvegicus

Organic Solvent Stability

Organic Solvent Comment Organism
Ethanol stable in presence of ethanol over long periods of time Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
epididymis
-
 Rattus norvegicus
-
fat pad
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
871
-
-
 Rattus norvegicus

Storage Stability

Storage Stability Organism
4°C, stable for several weeks Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
p-nitrophenyl phosphate + H2O
-
 Rattus norvegicus p-nitrophenol + phosphate
-
 ?
phosphoprotamine + H2O
-
 Rattus norvegicus protamine + phosphate
-
 ?
[3-hydroxy-3-methylglutaryl-CoA reductase]-phosphate + H2O
-
 Rattus norvegicus 3-hydroxy-3-methylglutaryl-CoA reductase + phosphate
-
 ?
[acetyl-CoA carboxylase]-phosphate + H2O
-
 Rattus norvegicus acetyl-CoA carboxylase + phosphate
-
 ?
[glycogen phosphorylase A]-phosphate
-
 Rattus norvegicus [glycogen phosphorylase A] + phosphate
-
 ?
[glycogen-phosphorylase a]-phosphate + H2O
-
 Rattus norvegicus glycogen-phosphorylase a + phosphate
-
 ?
[glycogen-synthase]-phosphate + H2O
-
 Rattus norvegicus glycogen-synthase + phosphate
-
 ?
[phosphoralase a]-phosphate + H2O
-
 Rattus norvegicus phosphoralase a + phosphate
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 71000, SDS-PAGE Rattus norvegicus