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Literature summary for 3.1.3.43 extracted from

  • Holness, M.J.; Sugden, M.C.
    Is there a role for pyruvate dehydrogenase-phosphatase in the re-activation of hepatic pyruvate dehydrogenase complex after re-feeding? (1988), Biochem. Soc. Trans., 16, 773-774.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
2-tetradecylglycidate together with insulin Rattus norvegicus
Dichloroacetate together with insulin Rattus norvegicus
Insulin with starved rats pretreated with dichloroacetate or 2-tetradecylglycidate Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O Rattus norvegicus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O
-
Rattus norvegicus [pyruvate dehydrogenase (lipoamide)] + phosphate
-
ir
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O
-
Rattus norvegicus ?
-
?