Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.3.4 extracted from

  • Park, Y.; Han, G.S.; Carman, G.M.
    A conserved tryptophan within the WRDPLVDID domain of yeast Pah1 phosphatidate phosphatase is required for its in vivo function in lipid metabolism (2017), J. Biol. Chem., 292, 19580-19589 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.3.4

Protein Variants

Protein Variants Comment Organism
W637A the mutant is not functional in vivo though the mutation does not compromise the PAH1-encoded enzyme activity Saccharomyces cerevisiae
W637E the mutant is not functional in vivo though the mutation does not compromise the PAH1-encoded enzyme activity Saccharomyces cerevisiae
W637F the mutation does not compromise the PAH1-encoded enzyme activity Saccharomyces cerevisiae
W637R the mutant is not functional in vivo though the mutation does not compromise the PAH1-encoded enzyme activity Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum membrane
-
 Saccharomyces cerevisiae 5789
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1,2-diacylglycerol 3-phosphate + H2O Saccharomyces cerevisiae
-
 1,2-diacyl-sn-glycerol + phosphate
-
 ?
1,2-diacylglycerol 3-phosphate + H2O Saccharomyces cerevisiae W303-1A
-
 1,2-diacyl-sn-glycerol + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P32567
-
-
Saccharomyces cerevisiae W303-1A P32567
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-diacylglycerol 3-phosphate + H2O
-
 Saccharomyces cerevisiae 1,2-diacyl-sn-glycerol + phosphate
-
 ?
1,2-diacylglycerol 3-phosphate + H2O
-
 Saccharomyces cerevisiae W303-1A 1,2-diacyl-sn-glycerol + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
pah1
-
 Saccharomyces cerevisiae
PAP
-
 Saccharomyces cerevisiae

General Information

General Information Comment Organism
metabolism the enzyme plays a major role in controlling the utilization of phosphatidate for the synthesis of triacylglycerol or membrane phospholipids Saccharomyces cerevisiae