Cloned (Comment) | Organism |
---|---|
overexpression in Spodoptera frugiperda Sf9 cells using the baculovirus expression system, and in Saccharomyces cerevisiae using multicopy plasmids | Saccharomyces cerevisiae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
diacylglycerol diphosphate | - |
Saccharomyces cerevisiae | |
NEM | - |
Saccharomyces cerevisiae | |
phosphatidic acid | substrate inhibition | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | lipid phosphate phosphatase enzymes possess a three-domain lipid phosphatase motif that is localized to the hydrophilic surface of the membrane | Saccharomyces cerevisiae | 16020 | - |
microsome | - |
Saccharomyces cerevisiae | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphatidic acid + H2O | Saccharomyces cerevisiae | lipid phosphate phosphatase enzymes may play a role in signal transduction by terminating signaling events of lipid phosphates | 1,2-diacylglycerol + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
gene llp1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme also shows diacylglycerol lipase activity, EC 3.1.1.34, overview | Saccharomyces cerevisiae | ? | - |
? | |
phosphatidic acid + H2O | lipid phosphate phosphatase enzymes may play a role in signal transduction by terminating signaling events of lipid phosphates | Saccharomyces cerevisiae | 1,2-diacylglycerol + phosphate | - |
? | |
phosphatidic acid + H2O | the conserved arginine residue in domain 1 and the conserved histidine residues in domains 2 and 3 are essential for catalytic activity | Saccharomyces cerevisiae | 1,2-diacylglycerol + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | lipid phosphate phosphatase enzymes possess a three-domain lipid phosphatase motif that is localized to the hydrophilic surface of the membrane, the conserved arginine residue in domain 1 and the conserved histidine residues in domains 2 and 3 are essential for catalytic activity | Saccharomyces cerevisiae |
Synonyms | Comment | Organism |
---|---|---|
lipid phosphate phosphatase | - |
Saccharomyces cerevisiae |
LLP1 | - |
Saccharomyces cerevisiae |
More | cf. EC 3.1.1.34 | Saccharomyces cerevisiae |
PA phosphatase | - |
Saccharomyces cerevisiae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Saccharomyces cerevisiae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
assay at | Saccharomyces cerevisiae |