Application | Comment | Organism |
---|---|---|
analysis | radiolabeled and fluorescent lipid substrates for the detection, quantitation and analysis of the enzymatic activities of the LPPs measured using intact or broken cell preparations as the source of enzyme | Mus musculus |
analysis | radiolabeled and fluorescent lipid substrates for the detection, quantitation and analysis of the enzymatic activities of the LPPs measured using intact or broken cell preparations as the source of enzyme | Homo sapiens |
analysis | radiolabeled and fluorescent lipid substrates for the detection, quantitation and analysis of the enzymatic activities of the LPPs measured using intact or broken cell preparations as the source of enzyme | Rattus norvegicus |
Cloned (Comment) | Organism |
---|---|
transient and stable overexpression in HEK-293 cells, baculovirus vectors for recombinant expression of LPPs in cultured Sf9 cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | insensitive to inhibition by the alkylating agent N-ethyl maleimide | Homo sapiens | |
additional information | insensitive to inhibition by the alkylating agent N-ethyl maleimide | Rattus norvegicus | |
propranolol | moderately effective inhibitor of LPP activity | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Mus musculus | 16020 | - |
membrane | - |
Homo sapiens | 16020 | - |
membrane | - |
Rattus norvegicus | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | independent of divalent metal ions | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | - |
Homo sapiens | - |
additional information | Swiss 3T3 cell | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ceramide 1-phosphate + H2O | - |
Homo sapiens | ceramide + phosphate | - |
? | |
ceramide 1-phosphate + H2O | - |
Rattus norvegicus | ceramide + phosphate | - |
? | |
lyso-phosphatidic acid + H2O | - |
Homo sapiens | monoacylglycerol + phosphate | - |
? | |
lyso-phosphatidic acid + H2O | - |
Rattus norvegicus | monoacylglycerol + phosphate | - |
? | |
phosphatidic acid + H2O | - |
Homo sapiens | diacylglycerol + phosphate | - |
? | |
phosphatidic acid + H2O | - |
Rattus norvegicus | diacylglycerol + phosphate | - |
? | |
sphingosine 1-phosphate + H2O | - |
Homo sapiens | sphingosine + phosphate | - |
? | |
sphingosine 1-phosphate + H2O | - |
Rattus norvegicus | sphingosine + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LPP1 | - |
Homo sapiens |
LPP2 | - |
Homo sapiens |
LPP3 | - |
Mus musculus |
LPP3 | - |
Homo sapiens |
LPP3 | - |
Rattus norvegicus |