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Literature summary for 3.1.3.4 extracted from

  • Kai, M.; Sakane, F.; Jia, Y.; Imai, S.; Yasuda, S.; Kanoh, H.
    Lipid phosphate phosphatases 1 and 3 are localized in distinct lipid rafts (2006), J. Biochem., 140, 677-686.
    View publication on PubMed
Search for more literature for 3.1.3.4

Activating Compound

Activating Compound Comment Organism Structure
androgen highly induces LPP1 expression in LNCaP cells Homo sapiens
methyltrienolone induces LPP1 expression Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
NIH3T3 cells stably expressing LPP1-CFP or LPP3-CFP. MDCK cells stably expressing LPP1-GFP and LPP3-GFP. COS-7 and PC-12 cells transiently expressing LPP1 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information CHAPS-insoluble LPP1 is resistant to the actin-disrupting drug cytochalasin D. CHAPS-resistant floating complexes containing LPP1 are sensitive to cholesterol depletion Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus CHAPS-resistant complexes containing LPP1 Homo sapiens 5794
-
membrane LPP1 and LPP3 are distributed in distinct lipid rafts that may provide unique microenvironments defining their non-redundant physiological functions. LPP1 is associated with rafts, which are segregated from those harboring LPP3, in a Triton-100-sensitive but CHAPS-resistant manner Homo sapiens 16020
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Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
LNCaP cell LPP1 Homo sapiens
-

Synonyms

Synonyms Comment Organism
lipid phosphate phosphatase 1
-
 Homo sapiens
lipid phosphate phosphatase 3
-
 Homo sapiens
LPP1
-
 Homo sapiens
LPP3
-
 Homo sapiens