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Literature summary for 3.1.3.4 extracted from

  • Yue, J.; Yokoyama, K.; Balazs, L.; Baker, D.L.; Smalley, D.; Pilquil, C.; Brindley, D.N.; Tigyi, G.
    Mice with transgenic overexpression of lipid phosphate phosphatase-1 display multiple organotypic deficits without alteration in circulating lysophosphatidate level (2004), Cell. Signal., 16, 385-399.
    View publication on PubMed
Search for more literature for 3.1.3.4

Cloned(Commentary)

Cloned (Comment) Organism
expression of the gene encoding the enzyme under control of chicken beta-actin promoter in mice embryos Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information construction of transgenic mice overexpressing the enzyme, the phenotype includes reduced body size, birth weight, and abnormalities in fur growth, decreased number of hair follicles, disrupted hair structure, and impaired spermatogenesis, phospholipid levels of mutants compared to wild-type mice, overview, ERK1/2 activation is not affected by enzyme overexpression Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Mus musculus 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus the enzyme regulates the level of phosphorylated lipids acting as growth factors or second messengers, the enzyme is involved in lipid signaling pathways ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast cell line immortalized cell line Mus musculus
-
liver
-
 Mus musculus
-
testis high enzyme activity Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme regulates the level of phosphorylated lipids acting as growth factors or second messengers, the enzyme is involved in lipid signaling pathways Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
lipid phosphate phosphatase-1
-
 Mus musculus
LPP-1
-
 Mus musculus