Protein Variants | Comment | Organism |
---|---|---|
additional information | SHIP-2 gene is knockdown in bone marrow-derived mast cells (BMMCs) by using the lentiviral-based RNA interference technique. Elimination results in both increased mast cell degranulation and cytokine (IL-4 and IL-13) gene expression upon FcepsilonRI stimulation. Absence of SHIP-2 results in increased activation of the small GTPase Rac-1 and in enhanced microtubule polymerization upon FcepsilonRI engagement | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
inositol 5'-phosphatase SHIP-2 | - |
Mus musculus |
SH2-domain containing inositol 5'-phosphatase | - |
Mus musculus |
SHIP2 | - |
Mus musculus |