General Stability | Organism |
---|---|
inactivated by freezing | Homo sapiens |
Triton X-100 stabilizes | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ammonyx LO | - |
Homo sapiens | |
Ca2+ | competitive with Mg2+ in presence of optimal concentrations of Mg2+ | Homo sapiens | |
hemoglobin | at concentrations higher than 1% W/v | Homo sapiens | |
neomycin | inhibits only in absence of Triton X-100 | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.27 | - |
phosphatidyl-myo-inositol 4,5-bisphosphate | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Homo sapiens | |
Mg2+ | Km: 0.012 mM | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
104000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.765 | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
4°C, half-life: about 1 day | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | no activity with 1-(3-sn-phosphatidyl)-D-myo-inositol 4-phosphate | Homo sapiens | ? | - |
? | |
myo-inositol 1,4,5-trisphosphate + H2O | - |
Homo sapiens | inositol 1,4-diphosphate + phosphate | - |
? | |
phosphatidyl-myo-inositol 4,5-bisphosphate + H2O | - |
Homo sapiens | phosphatidylinositol 4-phosphate + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 50000-53000, and a polypeptide of 100000-105000 Da at lower quantity | Homo sapiens |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
additional information | - |
activity declines sharply at temperatures above 37°C | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
4 | - |
half-life: about 1 day | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.8 | 8 | - |
Homo sapiens |