BRENDA - Enzyme Database
show all sequences of 3.1.3.31

Partial purification and properties of an acid nucleotidase from the postmicrosomal supernatant of rat spleen

Tjernshaugen, H.; Biochem. J. 169, 597-605 (1978)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
KF
cytosolic enzyme
Rattus norvegicus
Tartrate
cytosolic enzyme
Rattus norvegicus
Zn2+
-
Rattus norvegicus
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.7
-
3'-AMP
cytosolic enzyme
Rattus norvegicus
0.9
-
5'-AMP
cytosolic enzyme
Rattus norvegicus
1.7
-
3'-dAMP
cytosolic enzyme
Rattus norvegicus
1.7
-
3'-dGMP
cytosolic enzyme
Rattus norvegicus
1.7
-
3'-GMP
cytosolic enzyme
Rattus norvegicus
2.6
-
3'-dTMP
cytosolic enzyme
Rattus norvegicus
2.6
-
5'-dAMP
cytosolic enzyme
Rattus norvegicus
3.2
-
5'-dTMP
cytosolic enzyme
Rattus norvegicus
3.7
-
5'-CMP
cytosolic enzyme
Rattus norvegicus
4
-
p-nitrophenyl phosphate
cytosolic enzyme
Rattus norvegicus
4.7
-
5'-GMP
cytosolic enzyme
Rattus norvegicus
6.2
-
5'-dCMP
cytosolic enzyme
Rattus norvegicus
8
-
3'-dUMP
cytosolic enzyme
Rattus norvegicus
12
-
5'-dGMP
cytosolic enzyme
Rattus norvegicus
25
-
Glycerol 2-phosphate
cytosolic enzyme
Rattus norvegicus
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Rattus norvegicus
5829
-
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
125000
-
cytosolic enzyme, gel filtration
Rattus norvegicus
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Rattus norvegicus
-
-
-
Purification (Commentary)
Commentary
Organism
spleen cytosol
Rattus norvegicus
Source Tissue
Source Tissue
Commentary
Organism
Textmining
spleen
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.256
-
cytosolic enzyme
Rattus norvegicus
Storage Stability
Storage Stability
Organism
-20°C, 50 mM Tris-HCl buffer, pH 7.5, 1 mM dithiothreitol, 2 months
Rattus norvegicus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2',3'-cyclic-AMP + H2O
5% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
adenosine + phosphate
-
81066
Rattus norvegicus
?
2'-AMP + H2O
68% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
adenosine + phosphate
-
81066
Rattus norvegicus
?
2-glycerophosphate + H2O
cytosolic enzyme
81066
Rattus norvegicus
glycerol + phosphate
-
81066
Rattus norvegicus
?
3'-AMP + H2O
-
81066
Rattus norvegicus
adenosine + phosphate
-
81066
Rattus norvegicus
?
3'-CMP + H2O
-
81066
Rattus norvegicus
cytidine + phosphate
-
81066
Rattus norvegicus
?
3'-dAMP + H2O
131% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
3'-deoxyadenosine + phosphate
-
81066
Rattus norvegicus
?
3'-dAMP + H2O
i.e. 2'-deoxyadenosine 3'-phosphate
81066
Rattus norvegicus
3'-deoxyadenosine + phosphate
-
81066
Rattus norvegicus
?
3'-dCMP + H2O
101% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxycytidine + phosphate
-
81066
Rattus norvegicus
?
3'-dCMP + H2O
i.e. 2'-deoxycytidine 3'-phosphate
81066
Rattus norvegicus
deoxycytidine + phosphate
-
81066
Rattus norvegicus
?
3'-dTMP + H2O
77% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxythymidine + phosphate
-
81066
Rattus norvegicus
?
3'-dTMP + H2O
i.e. 2'-deoxythymidine 3'-phosphate
81066
Rattus norvegicus
deoxythymidine + phosphate
-
81066
Rattus norvegicus
?
3'-dUMP + H2O
-
81066
Rattus norvegicus
deoxyuridine + phosphate
-
-
-
-
3'-GMP + H2O
49% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
guanosine + phosphate
-
81066
Rattus norvegicus
?
3'-UMP + H2O
14% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
uridine + phosphate
-
81066
Rattus norvegicus
?
5'-AMP + H2O
49% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
adenosine + phosphate
-
81066
Rattus norvegicus
?
5'-CMP + H2O
97% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
cytidine + phosphate
-
81066
Rattus norvegicus
?
5'-dAMP + H2O
128% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxyadenosine + phosphate
-
81066
Rattus norvegicus
?
5'-dAMP + H2O
i.e. 2'-deoxyadenosine 5'-phosphate
81066
Rattus norvegicus
deoxyadenosine + phosphate
-
81066
Rattus norvegicus
?
5'-dCMP + H2O
i.e. 2'-deoxycytidine 5'-phosphate
81066
Rattus norvegicus
deoxycytidine + phosphate
-
81066
Rattus norvegicus
?
5'-dGMP + H2O
142% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxyguanosine + phosphate
-
81066
Rattus norvegicus
?
5'-dGMP + H2O
i.e. 2'-deoxyguanosine 5'-phosphate
81066
Rattus norvegicus
deoxyguanosine + phosphate
-
81066
Rattus norvegicus
?
5'-dIMP + H2O
46% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxyinosine + phosphate
-
81066
Rattus norvegicus
?
5'-dIMP + H2O
i.e. 2'-deoxyinosine 5'-phosphate
81066
Rattus norvegicus
deoxyinosine + phosphate
-
81066
Rattus norvegicus
?
5'-dTMP + H2O
60% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxythymidine + phosphate
-
81066
Rattus norvegicus
?
5'-dTMP + H2O
i.e. 2'-deoxythymidine 5'-phosphate
81066
Rattus norvegicus
deoxythymidine + phosphate
-
81066
Rattus norvegicus
?
5'-dUMP + H2O
28% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxyuridine + phosphate
-
81066
Rattus norvegicus
?
5'-dUMP + H2O
i.e. 2'-deoxyuridine 5'-phosphate
81066
Rattus norvegicus
deoxyuridine + phosphate
-
81066
Rattus norvegicus
?
5'-GMP + H2O
31% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
guanosine + phosphate
-
81066
Rattus norvegicus
?
5'-IMP + H2O
28% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
inosine + phosphate
-
81066
Rattus norvegicus
?
5'-UMP + H2O
22% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
uridine + phosphate
-
81066
Rattus norvegicus
?
ATP + H2O
40% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
?
-
-
-
?
p-nitrophenyl phosphate + H2O
140% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
p-nitrophenol + phosphate
-
81066
Rattus norvegicus
?
Temperature Stability [°C]
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
additional information
-
serum albumin or dithiothreitol stabilizes cytosolic enzyme at 37°C
Rattus norvegicus
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
4
5
cytosolic enzyme, absence of Mg2+, substrates 3'-AMP and 3'-dAMP
Rattus norvegicus
5.5
-
cytosolic enzyme, presence of Mg2+, substrate 3'-dCMP
Rattus norvegicus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
KF
cytosolic enzyme
Rattus norvegicus
Tartrate
cytosolic enzyme
Rattus norvegicus
Zn2+
-
Rattus norvegicus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.7
-
3'-AMP
cytosolic enzyme
Rattus norvegicus
0.9
-
5'-AMP
cytosolic enzyme
Rattus norvegicus
1.7
-
3'-dAMP
cytosolic enzyme
Rattus norvegicus
1.7
-
3'-dGMP
cytosolic enzyme
Rattus norvegicus
1.7
-
3'-GMP
cytosolic enzyme
Rattus norvegicus
2.6
-
3'-dTMP
cytosolic enzyme
Rattus norvegicus
2.6
-
5'-dAMP
cytosolic enzyme
Rattus norvegicus
3.2
-
5'-dTMP
cytosolic enzyme
Rattus norvegicus
3.7
-
5'-CMP
cytosolic enzyme
Rattus norvegicus
4
-
p-nitrophenyl phosphate
cytosolic enzyme
Rattus norvegicus
4.7
-
5'-GMP
cytosolic enzyme
Rattus norvegicus
6.2
-
5'-dCMP
cytosolic enzyme
Rattus norvegicus
8
-
3'-dUMP
cytosolic enzyme
Rattus norvegicus
12
-
5'-dGMP
cytosolic enzyme
Rattus norvegicus
25
-
Glycerol 2-phosphate
cytosolic enzyme
Rattus norvegicus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Rattus norvegicus
5829
-
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
125000
-
cytosolic enzyme, gel filtration
Rattus norvegicus
Purification (Commentary) (protein specific)
Commentary
Organism
spleen cytosol
Rattus norvegicus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
spleen
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.256
-
cytosolic enzyme
Rattus norvegicus
Storage Stability (protein specific)
Storage Stability
Organism
-20°C, 50 mM Tris-HCl buffer, pH 7.5, 1 mM dithiothreitol, 2 months
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2',3'-cyclic-AMP + H2O
5% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
adenosine + phosphate
-
81066
Rattus norvegicus
?
2'-AMP + H2O
68% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
adenosine + phosphate
-
81066
Rattus norvegicus
?
2-glycerophosphate + H2O
cytosolic enzyme
81066
Rattus norvegicus
glycerol + phosphate
-
81066
Rattus norvegicus
?
3'-AMP + H2O
-
81066
Rattus norvegicus
adenosine + phosphate
-
81066
Rattus norvegicus
?
3'-CMP + H2O
-
81066
Rattus norvegicus
cytidine + phosphate
-
81066
Rattus norvegicus
?
3'-dAMP + H2O
131% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
3'-deoxyadenosine + phosphate
-
81066
Rattus norvegicus
?
3'-dAMP + H2O
i.e. 2'-deoxyadenosine 3'-phosphate
81066
Rattus norvegicus
3'-deoxyadenosine + phosphate
-
81066
Rattus norvegicus
?
3'-dCMP + H2O
101% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxycytidine + phosphate
-
81066
Rattus norvegicus
?
3'-dCMP + H2O
i.e. 2'-deoxycytidine 3'-phosphate
81066
Rattus norvegicus
deoxycytidine + phosphate
-
81066
Rattus norvegicus
?
3'-dTMP + H2O
77% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxythymidine + phosphate
-
81066
Rattus norvegicus
?
3'-dTMP + H2O
i.e. 2'-deoxythymidine 3'-phosphate
81066
Rattus norvegicus
deoxythymidine + phosphate
-
81066
Rattus norvegicus
?
3'-dUMP + H2O
-
81066
Rattus norvegicus
deoxyuridine + phosphate
-
-
-
-
3'-GMP + H2O
49% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
guanosine + phosphate
-
81066
Rattus norvegicus
?
3'-UMP + H2O
14% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
uridine + phosphate
-
81066
Rattus norvegicus
?
5'-AMP + H2O
49% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
adenosine + phosphate
-
81066
Rattus norvegicus
?
5'-CMP + H2O
97% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
cytidine + phosphate
-
81066
Rattus norvegicus
?
5'-dAMP + H2O
128% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxyadenosine + phosphate
-
81066
Rattus norvegicus
?
5'-dAMP + H2O
i.e. 2'-deoxyadenosine 5'-phosphate
81066
Rattus norvegicus
deoxyadenosine + phosphate
-
81066
Rattus norvegicus
?
5'-dCMP + H2O
i.e. 2'-deoxycytidine 5'-phosphate
81066
Rattus norvegicus
deoxycytidine + phosphate
-
81066
Rattus norvegicus
?
5'-dGMP + H2O
142% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxyguanosine + phosphate
-
81066
Rattus norvegicus
?
5'-dGMP + H2O
i.e. 2'-deoxyguanosine 5'-phosphate
81066
Rattus norvegicus
deoxyguanosine + phosphate
-
81066
Rattus norvegicus
?
5'-dIMP + H2O
46% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxyinosine + phosphate
-
81066
Rattus norvegicus
?
5'-dIMP + H2O
i.e. 2'-deoxyinosine 5'-phosphate
81066
Rattus norvegicus
deoxyinosine + phosphate
-
81066
Rattus norvegicus
?
5'-dTMP + H2O
60% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxythymidine + phosphate
-
81066
Rattus norvegicus
?
5'-dTMP + H2O
i.e. 2'-deoxythymidine 5'-phosphate
81066
Rattus norvegicus
deoxythymidine + phosphate
-
81066
Rattus norvegicus
?
5'-dUMP + H2O
28% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
deoxyuridine + phosphate
-
81066
Rattus norvegicus
?
5'-dUMP + H2O
i.e. 2'-deoxyuridine 5'-phosphate
81066
Rattus norvegicus
deoxyuridine + phosphate
-
81066
Rattus norvegicus
?
5'-GMP + H2O
31% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
guanosine + phosphate
-
81066
Rattus norvegicus
?
5'-IMP + H2O
28% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
inosine + phosphate
-
81066
Rattus norvegicus
?
5'-UMP + H2O
22% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
uridine + phosphate
-
81066
Rattus norvegicus
?
ATP + H2O
40% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
?
-
-
-
?
p-nitrophenyl phosphate + H2O
140% of the activity of 3'-AMP, cytosolic enzyme
81066
Rattus norvegicus
p-nitrophenol + phosphate
-
81066
Rattus norvegicus
?
Temperature Stability [°C] (protein specific)
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
additional information
-
serum albumin or dithiothreitol stabilizes cytosolic enzyme at 37°C
Rattus norvegicus
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
4
5
cytosolic enzyme, absence of Mg2+, substrates 3'-AMP and 3'-dAMP
Rattus norvegicus
5.5
-
cytosolic enzyme, presence of Mg2+, substrate 3'-dCMP
Rattus norvegicus
Other publictions for EC 3.1.3.31
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
750046
Kozarski
7-Methylguanosine monophospha ...
Homo sapiens
Bioorg. Med. Chem.
26
191-199
2018
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-
1
-
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1
-
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1
-
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1
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-
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2
-
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-
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1
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-
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1
-
-
-
-
-
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1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
750791
Trundova
Highly stable single-strand-s ...
Legionella pneumophila subsp. pneumophila, Legionella pneumophila subsp. pneumophila Philadelphia 1
Int. J. Biol. Macromol.
114
776-787
2018
-
-
1
-
-
-
1
1
1
-
1
-
-
6
-
-
1
-
-
-
-
-
4
1
-
-
-
-
1
-
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-
1
-
-
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1
-
-
-
-
-
1
1
1
1
-
1
-
-
-
-
1
-
-
-
-
4
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
749534
Salman
Characterization of ectonucle ...
Rattus norvegicus
Am. J. Physiol. Cell Physiol.
313
C274-C284
2017
-
-
-
-
-
-
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-
1
-
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1
-
2
-
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2
-
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1
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1
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1
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2
-
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1
-
-
-
-
-
-
-
-
-
2
-
-
2
-
-
750037
Fiene
Inhibitors for the bacterial ...
Legionella pneumophila 130b, Legionella pneumophila
Bioorg. Med. Chem.
24
4363-4371
2016
-
-
1
-
-
-
25
-
-
-
-
4
-
7
-
-
1
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
5
-
2
-
-
1
-
-
-
-
2
25
5
-
-
-
-
4
-
-
-
1
-
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6
-
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-
-
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751345
Luchter-Wasylewska
-
Homotropic allostery of nucle ...
Homo sapiens
J. Mol. Catal. B
128
73-77
2016
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-
-
-
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4
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4
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751279
Laketa
Brain injury alters ectonucle ...
Rattus norvegicus
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2015
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3
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1
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1
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751403
Cabello-Diaz
Identification and characteri ...
Phaseolus vulgaris
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7
1
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2
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1
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1
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729545
Bageritz
Stem cell characteristics in g ...
Homo sapiens
Cell Death Differ.
21
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2014
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1
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1
1
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729691
Prunetti
Structural and biochemical pro ...
Haloferax volcanii, Haloferax volcanii DS2
Extremophiles
18
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2013
1
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1
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1
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1
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9
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6
1
1
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716430
Zarlenga
A calcium-activated nucleotida ...
Ostertagia ostertagi, Ostertagia ostertagi L4
Parasitology
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333-343
2011
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8
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1
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691895
Jensen
ATP release and extracellular ...
Oncorhynchus mykiss
Comp. Biochem. Physiol. A
152
351-356
2009
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1
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694690
Wilson
The nucleotidase/phosphatase S ...
Arabidopsis thaliana
Plant J.
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2009
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1
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678347
Yang
Characterization and importanc ...
Homo sapiens
Biochemistry
47
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2008
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1
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4
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5
1
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2
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1
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7
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1
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1
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7
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682900
Yang
Engineered human soluble calci ...
Cimex lectularius, Homo sapiens
Thromb. Res.
122
541-548
2008
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-
2
-
2
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2
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7
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2
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3
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8
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3
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8
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691000
Ivanenkov
Trafficking and intracellular ...
Homo sapiens
Biochemistry
47
9184-9197
2008
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-
1
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4
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2
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1
1
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1
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1
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4
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1
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1
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1
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691559
Ghisleni
Selenium compounds counteract ...
Rattus norvegicus
Brain Res.
1221
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2008
1
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1
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2
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2
1
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2
1
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-
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-
-
-
691919
Sales
-
Nucleotidase and DNase activit ...
Bothrops alcatraz, Bothrops alternatus, Bothrops atrox, Bothrops brazili, Bothrops cotiara, Bothrops diporus, Bothrops erythromelas, Bothrops fonsecai, Bothrops insularis, Bothrops itapetiningae, Bothrops jararaca, Bothrops jararacussu, Bothrops marajoensis, Bothrops matogrossensis, Bothrops moojeni, Bothrops neuwiedi, Bothrops pauloensis, Bothrops pirajai, Bothrops pradoi, Bothrops pubescens, Bothrops taeniatus, Crotalus adamanteus, Crotalus durissus, Crotalus durissus cumanensis, Lachesis muta, Micrurus frontalis, no activity in Loxosceles gaucho, no activity in Philodryas olfersii
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147C
85-95
2008
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26
-
26
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26
-
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692192
Pedrazza
Ecto-nucleotidase pathway is a ...
Rattus norvegicus, Rattus norvegicus Wistar
Eur. J. Pharmacol.
583
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2008
2
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2
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2
1
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2
1
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4
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694864
Frederick
A role for a lithium-inhibited ...
Mus musculus
Proc. Natl. Acad. Sci. USA
105
11605-11612
2008
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1
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2
2
1
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2
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1
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15
3
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1
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1
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2
2
1
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1
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15
3
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1
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729916
Zhou
Proteasomal components require ...
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8096-8105
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-
2
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-
1
1
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665044
Devader
Xenopus apyrase (xapy), a secr ...
Xenopus laevis
Gene
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135-141
2006
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1
-
-
-
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1
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4
-
6
-
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1
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4
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1
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1
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1
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4
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680687
Yang
Calcium-dependent dimerization ...
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2006
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1
1
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2
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1
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1
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1
1
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1
-
1
8
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3
2
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1
1
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-
1
1
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-
-
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-
-
-
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681602
Yegutkin
Intravascular ADP and soluble ...
Homo sapiens
J. Physiol.
579
553-564
2006
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-
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-
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1
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1
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1
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1
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656266
Proudfoot
General Enzymatic Screens Iden ...
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12
18
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5
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1
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15
2
1
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18
3
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4
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-
-
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-
12
4
18
-
6
5
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1
-
15
2
1
-
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18
3
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-
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-
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664646
Borges
-
Nucleotidase activities in mem ...
Helix aspersa
Comp. Biochem. Physiol. B
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2004
3
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3
4
1
2
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1
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1
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8
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1
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2
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3
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3
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4
1
2
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2
1
-
8
-
1
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-
2
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-
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654871
Passariello
The molecular class C acid pho ...
Elizabethkingia meningoseptica
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203-209
2003
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1
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1
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10
10
1
2
2
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4
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1
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1
-
10
1
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-
10
1
1
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9
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1
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1
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9
10
-
10
1
2
2
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1
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1
-
10
1
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10
1
1
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656785
Vance
Repair of DNA strand breaks by ...
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1
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1
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2
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654913
Tikhaya
-
Biochemical adaptation of barl ...
Hordeum vulgare
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Nikbakht
Complex hippocampal responses ...
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Cytoplasmic 5'(3')-nucleotidas ...
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Skladanowski
Partial purification and prope ...
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Yokoyama
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Purification and characterizat ...
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Cellular localization and deve ...
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9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81061
Tjernshaugen
Activity of deoxyinosine-activ ...
Homo sapiens, Oryctolagus cuniculus, Rattus norvegicus
Int. J. Biochem.
13
417-421
1981
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
18
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
18
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81063
Simonis
Studies on a membrane-bound nu ...
uncultured marine bacterium
Int. J. Biochem.
13
733-738
1981
-
-
-
-
-
-
-
23
1
3
-
-
-
2
-
-
-
-
-
-
-
-
22
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
23
1
3
-
-
-
-
-
-
-
-
-
-
22
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81062
Tjershaugen
-
Deoxyadenosine-activated nucle ...
Rattus norvegicus
Acta Chem. Scand. B
33
384-390
1979
5
-
-
-
-
-
-
2
-
-
1
-
-
1
-
-
1
-
-
1
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
1
-
1
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
81064
Delaunay
Properties of a non-specific n ...
Oryctolagus cuniculus
Biochim. Biophys. Acta
527
425-431
1978
-
-
-
-
-
-
2
5
2
2
-
-
-
2
-
-
-
-
-
1
1
-
15
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
5
2
2
-
-
-
-
-
-
-
1
1
-
15
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
81065
Arsenis
An acid nucleotidase from rat ...
Rattus norvegicus
Methods Enzymol.
51
271-275
1978
-
-
-
-
-
-
8
3
2
-
-
-
-
2
-
-
1
-
-
2
1
-
6
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
8
-
3
2
-
-
-
-
-
-
1
-
2
1
-
6
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
81066
Tjernshaugen
Partial purification and prope ...
Rattus norvegicus
Biochem. J.
169
597-605
1978
-
-
-
-
-
-
3
15
1
-
1
-
-
2
-
-
1
-
-
2
1
1
32
-
-
-
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
15
1
-
1
-
-
-
-
1
-
2
1
1
32
-
-
-
1
-
2
-
-
-
-
-
-
-
-
-
81067
Schrader
Membrane-bound nucleotidase of ...
Bacillus cereus
J. Bacteriol.
133
576-583
1978
-
-
-
-
-
-
-
-
1
1
1
-
-
3
-
-
1
-
-
-
1
-
15
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
1
-
-
-
-
1
-
-
1
-
15
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
81068
Tjernshaugen
Subcellular distribution and a ...
Rattus norvegicus
Biochem. J.
154
77-80
1976
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
16
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
16
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81069
Fritzson
Kinetic analysis of a rat-live ...
Rattus norvegicus
Eur. J. Biochem.
38
408-415
1973
11
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
11
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81070
Fritzson
Regulation of rat-liver nucleo ...
Rattus norvegicus
Eur. J. Biochem.
27
38-42
1972
3
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81071
Fritzson
A new nucleotidase of rat live ...
Rattus norvegicus
Biochim. Biophys. Acta
235
128-141
1971
-
-
-
-
-
1
-
7
1
-
1
-
-
2
-
-
1
-
-
2
2
1
9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
7
1
-
1
-
-
-
-
1
-
2
2
1
9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81072
Arsenis
Purification and properties of ...
Rattus norvegicus
J. Biol. Chem.
243
5702-5708
1968
-
-
-
-
-
-
3
-
2
1
1
-
-
2
-
-
1
-
-
2
1
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
2
1
1
-
-
-
-
1
-
2
1
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-