BRENDA - Enzyme Database
show all sequences of 3.1.3.31

General Enzymatic Screens Identify Three New Nucleotidases in Escherichia coli. Biochemical Characterization of SurE, YfbR, and Yjjg

Proudfoot, M.; Kuznetsova, E.; Brown, G.; Rao, N.N.; Kitagawa, M.; Mori, H.; Savchenko, A.; Yakunin, A.F.; J. Biol. Chem. 279, 54687-54694 (2004)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
ADP
inhibits SurE slightly, YfbR, not YjjG, competitive
Escherichia coli
ATP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
CTP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
dATP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
dCTP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
dGTP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
dTTP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
GTP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
ITP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
additional information
inhibitory potency of nucleotides, overview, AMP is a poor inhibitor for SurE, YfbR, and YjjG, YjjG is not inhibitable by nucleotides
Escherichia coli
TTP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
UTP
inhibits SurE, YfbR, and slightly YjjG, competitive
Escherichia coli
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.008
-
5'-dTMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.012
-
5'-dAMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.017
-
5'-dIMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.02
-
5'-dUMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.02
-
Polyphosphate
pH 7.0, 37°C, SurE, with Mg2+
Escherichia coli
0.036
-
5'-dCMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.047
-
5'-dGMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.1
-
3'-AMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
0.26
-
5'-GMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
0.28
-
5'-dGMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
0.32
-
5'-AMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
0.37
-
3'-CMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
0.51
-
5'-dTMP
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
0.66
-
5'-UMP
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
0.77
-
5'-dUMP
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
2.09
-
4-nitrophenyl phosphate
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
2.49
-
4-nitrophenyl phosphate
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
17.8
-
4-nitrophenyl phosphate
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Co2+
preferred by YfbR, activates SurE, YfbR, and YjjG
Escherichia coli
Cu2+
activates YfbR
Escherichia coli
Mg2+
preferred by YjjG, activates SurE and YjjG
Escherichia coli
Mn2+
preferred by SurE, activates SurE, YfbR, and YjjG
Escherichia coli
additional information
dependent on divalent cations: SurE prefers Mn2+ to Co2+, Ni2+, and Mg2+, YfbR prefers Co2+ to Mn2+ and Cu2+, YjjG prefers Mg2+ to Mn2+ and Co2+, in descending orders, overview
Escherichia coli
Ni2+
activates SurE
Escherichia coli
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
35700
-
monomeric YjjG, gel filtration
Escherichia coli
41600
-
monomeric SurE, gel filtration
Escherichia coli
52800
-
dimeric YjjG, gel filtration
Escherichia coli
71300
-
trimeric YfbR, gel filtration
Escherichia coli
100000
-
above, tetrameric YjjG and YfbR, gel filtration
Escherichia coli
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Escherichia coli
-
genes surE, yfbR, and yjjG
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
additional information
-
-
Escherichia coli
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3'-AMP + H2O
-
656266
Escherichia coli
adenosine + phosphate
-
-
-
?
3'-CMP + H2O
-
656266
Escherichia coli
cytosine + phosphate
-
-
-
?
4-nitrophenyl phosphate + H2O
-
656266
Escherichia coli
4-nitrophenol + phosphate
-
-
-
?
5'-AMP + H2O
-
656266
Escherichia coli
adenosine + phosphate
-
-
-
?
5'-CMP + H2O
-
656266
Escherichia coli
cytidine + phosphate
-
-
-
?
5'-dAMP + H2O
-
656266
Escherichia coli
deoxyadenosine + phosphate
-
-
-
?
5'-dCMP + H2O
-
656266
Escherichia coli
2'-deoxycytidine + phosphate
-
-
-
?
5'-dGMP + H2O
-
656266
Escherichia coli
deoxyguanosine + phosphate
-
-
-
?
5'-dIMP + H2O
YfbR
656266
Escherichia coli
hypoxanthine + phosphate
-
-
-
?
5'-dTMP + H2O
-
656266
Escherichia coli
deoxythymidine + phosphate
-
-
-
?
5'-dUMP + H2O
-
656266
Escherichia coli
deoxyuridine + phosphate
-
-
-
-
5'-GMP + H2O
-
656266
Escherichia coli
guanosine + phosphate
-
-
-
?
5'-TMP + H2O
-
656266
Escherichia coli
thymidine + phosphate
-
-
-
?
additional information
substrate specificities of SurE, YfbR, and YjjG, overview
656266
Escherichia coli
?
-
-
-
-
polyphosphate + H2O
SurE
656266
Escherichia coli
phosphate
-
-
-
?
Subunits
Subunits
Commentary
Organism
More
SurE, YfbR, and YjjG show monomeric, dimeric, trimeric, and tetrameric forms, overview
Escherichia coli
oligomer
x * 35700, YjjG, SDS-PAGE and gel filtration, x * 41600, SurE, SDS-PAGE and gel filtration
Escherichia coli
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
37
-
assay at
Escherichia coli
Turnover Number [1/s]
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
0.05
-
Polyphosphate
pH 7.0, 37°C, SurE, with Mg2+
Escherichia coli
0.16
-
5'-dTMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.2
-
5'-dGMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.23
-
5'-dCMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.23
-
5'-dUMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.24
-
5'-dIMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.3
-
5'-dAMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.56
-
4-nitrophenyl phosphate
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
3.55
-
4-nitrophenyl phosphate
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
4.1
-
4-nitrophenyl phosphate
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
4.9
-
5'-AMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
5.93
-
3'-CMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
8.04
-
5'-dGMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
9.84
-
3'-AMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
11
-
5'-GMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
21.4
-
5'-dUMP
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
30.4
-
5'-dTMP
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
34.2
-
5'-UMP
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
-
SurE
Escherichia coli
7.5
-
YjjG
Escherichia coli
8
-
YfbR
Escherichia coli
Ki Value [mM]
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
0.0013
-
ADP
pH 8.0, 37°C, YfbR, versus 5'-dAMP, with Co2+
Escherichia coli
0.0014
-
dATP
pH 8.0, 37°C, YfbR, versus 5'-dAMP, with Co2+
Escherichia coli
0.0017
-
ATP
pH 8.0, 37°C, YfbR, versus 5'-dAMP, with Co2+
Escherichia coli
0.024
-
ATP
pH 7.0, 37°C, SurE, versus 3'-AMP, with Mn2+
Escherichia coli
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
ADP
inhibits SurE slightly, YfbR, not YjjG, competitive
Escherichia coli
ATP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
CTP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
dATP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
dCTP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
dGTP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
dTTP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
GTP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
ITP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
additional information
inhibitory potency of nucleotides, overview, AMP is a poor inhibitor for SurE, YfbR, and YjjG, YjjG is not inhibitable by nucleotides
Escherichia coli
TTP
inhibits SurE, YfbR, not YjjG, competitive
Escherichia coli
UTP
inhibits SurE, YfbR, and slightly YjjG, competitive
Escherichia coli
Ki Value [mM] (protein specific)
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
0.0013
-
ADP
pH 8.0, 37°C, YfbR, versus 5'-dAMP, with Co2+
Escherichia coli
0.0014
-
dATP
pH 8.0, 37°C, YfbR, versus 5'-dAMP, with Co2+
Escherichia coli
0.0017
-
ATP
pH 8.0, 37°C, YfbR, versus 5'-dAMP, with Co2+
Escherichia coli
0.024
-
ATP
pH 7.0, 37°C, SurE, versus 3'-AMP, with Mn2+
Escherichia coli
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.008
-
5'-dTMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.012
-
5'-dAMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.017
-
5'-dIMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.02
-
5'-dUMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.02
-
Polyphosphate
pH 7.0, 37°C, SurE, with Mg2+
Escherichia coli
0.036
-
5'-dCMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.047
-
5'-dGMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.1
-
3'-AMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
0.26
-
5'-GMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
0.28
-
5'-dGMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
0.32
-
5'-AMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
0.37
-
3'-CMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
0.51
-
5'-dTMP
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
0.66
-
5'-UMP
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
0.77
-
5'-dUMP
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
2.09
-
4-nitrophenyl phosphate
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
2.49
-
4-nitrophenyl phosphate
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
17.8
-
4-nitrophenyl phosphate
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Co2+
preferred by YfbR, activates SurE, YfbR, and YjjG
Escherichia coli
Cu2+
activates YfbR
Escherichia coli
Mg2+
preferred by YjjG, activates SurE and YjjG
Escherichia coli
Mn2+
preferred by SurE, activates SurE, YfbR, and YjjG
Escherichia coli
additional information
dependent on divalent cations: SurE prefers Mn2+ to Co2+, Ni2+, and Mg2+, YfbR prefers Co2+ to Mn2+ and Cu2+, YjjG prefers Mg2+ to Mn2+ and Co2+, in descending orders, overview
Escherichia coli
Ni2+
activates SurE
Escherichia coli
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
35700
-
monomeric YjjG, gel filtration
Escherichia coli
41600
-
monomeric SurE, gel filtration
Escherichia coli
52800
-
dimeric YjjG, gel filtration
Escherichia coli
71300
-
trimeric YfbR, gel filtration
Escherichia coli
100000
-
above, tetrameric YjjG and YfbR, gel filtration
Escherichia coli
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
additional information
-
-
Escherichia coli
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3'-AMP + H2O
-
656266
Escherichia coli
adenosine + phosphate
-
-
-
?
3'-CMP + H2O
-
656266
Escherichia coli
cytosine + phosphate
-
-
-
?
4-nitrophenyl phosphate + H2O
-
656266
Escherichia coli
4-nitrophenol + phosphate
-
-
-
?
5'-AMP + H2O
-
656266
Escherichia coli
adenosine + phosphate
-
-
-
?
5'-CMP + H2O
-
656266
Escherichia coli
cytidine + phosphate
-
-
-
?
5'-dAMP + H2O
-
656266
Escherichia coli
deoxyadenosine + phosphate
-
-
-
?
5'-dCMP + H2O
-
656266
Escherichia coli
2'-deoxycytidine + phosphate
-
-
-
?
5'-dGMP + H2O
-
656266
Escherichia coli
deoxyguanosine + phosphate
-
-
-
?
5'-dIMP + H2O
YfbR
656266
Escherichia coli
hypoxanthine + phosphate
-
-
-
?
5'-dTMP + H2O
-
656266
Escherichia coli
deoxythymidine + phosphate
-
-
-
?
5'-dUMP + H2O
-
656266
Escherichia coli
deoxyuridine + phosphate
-
-
-
-
5'-GMP + H2O
-
656266
Escherichia coli
guanosine + phosphate
-
-
-
?
5'-TMP + H2O
-
656266
Escherichia coli
thymidine + phosphate
-
-
-
?
additional information
substrate specificities of SurE, YfbR, and YjjG, overview
656266
Escherichia coli
?
-
-
-
-
polyphosphate + H2O
SurE
656266
Escherichia coli
phosphate
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
More
SurE, YfbR, and YjjG show monomeric, dimeric, trimeric, and tetrameric forms, overview
Escherichia coli
oligomer
x * 35700, YjjG, SDS-PAGE and gel filtration, x * 41600, SurE, SDS-PAGE and gel filtration
Escherichia coli
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
37
-
assay at
Escherichia coli
Turnover Number [1/s] (protein specific)
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
0.05
-
Polyphosphate
pH 7.0, 37°C, SurE, with Mg2+
Escherichia coli
0.16
-
5'-dTMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.2
-
5'-dGMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.23
-
5'-dCMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.23
-
5'-dUMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.24
-
5'-dIMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.3
-
5'-dAMP
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
0.56
-
4-nitrophenyl phosphate
pH 8.0, 37°C, YfbR, with Co2+
Escherichia coli
3.55
-
4-nitrophenyl phosphate
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
4.1
-
4-nitrophenyl phosphate
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
4.9
-
5'-AMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
5.93
-
3'-CMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
8.04
-
5'-dGMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
9.84
-
3'-AMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
11
-
5'-GMP
pH 7.0, 37°C, SurE, with Mn2+
Escherichia coli
21.4
-
5'-dUMP
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
30.4
-
5'-dTMP
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
34.2
-
5'-UMP
pH 7.5, 37°C, YjjG, with Mn2+
Escherichia coli
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
-
SurE
Escherichia coli
7.5
-
YjjG
Escherichia coli
8
-
YfbR
Escherichia coli
Other publictions for EC 3.1.3.31
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
750046
Kozarski
7-Methylguanosine monophospha ...
Homo sapiens
Bioorg. Med. Chem.
26
191-199
2018
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-
1
-
-
-
-
-
1
-
-
-
-
1
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
750791
Trundova
Highly stable single-strand-s ...
Legionella pneumophila subsp. pneumophila, Legionella pneumophila subsp. pneumophila Philadelphia 1
Int. J. Biol. Macromol.
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-
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1
1
-
1
-
-
6
-
-
1
-
-
-
-
-
4
1
-
-
-
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
1
1
1
-
1
-
-
-
-
1
-
-
-
-
4
1
-
-
-
-
1
-
-
-
-
-
-
-
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-
749534
Salman
Characterization of ectonucle ...
Rattus norvegicus
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750037
Fiene
Inhibitors for the bacterial ...
Legionella pneumophila 130b, Legionella pneumophila
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751345
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Homotropic allostery of nucle ...
Homo sapiens
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2016
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751279
Laketa
Brain injury alters ectonucle ...
Rattus norvegicus
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2015
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751403
Cabello-Diaz
Identification and characteri ...
Phaseolus vulgaris
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2015
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729545
Bageritz
Stem cell characteristics in g ...
Homo sapiens
Cell Death Differ.
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2014
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729691
Prunetti
Structural and biochemical pro ...
Haloferax volcanii, Haloferax volcanii DS2
Extremophiles
18
283-293
2013
1
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9
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716430
Zarlenga
A calcium-activated nucleotida ...
Ostertagia ostertagi, Ostertagia ostertagi L4
Parasitology
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2011
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691895
Jensen
ATP release and extracellular ...
Oncorhynchus mykiss
Comp. Biochem. Physiol. A
152
351-356
2009
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694690
Wilson
The nucleotidase/phosphatase S ...
Arabidopsis thaliana
Plant J.
58
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2009
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678347
Yang
Characterization and importanc ...
Homo sapiens
Biochemistry
47
771-778
2008
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1
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682900
Yang
Engineered human soluble calci ...
Cimex lectularius, Homo sapiens
Thromb. Res.
122
541-548
2008
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2
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2
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691000
Ivanenkov
Trafficking and intracellular ...
Homo sapiens
Biochemistry
47
9184-9197
2008
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4
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691559
Ghisleni
Selenium compounds counteract ...
Rattus norvegicus
Brain Res.
1221
134-140
2008
1
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691919
Sales
-
Nucleotidase and DNase activit ...
Bothrops alcatraz, Bothrops alternatus, Bothrops atrox, Bothrops brazili, Bothrops cotiara, Bothrops diporus, Bothrops erythromelas, Bothrops fonsecai, Bothrops insularis, Bothrops itapetiningae, Bothrops jararaca, Bothrops jararacussu, Bothrops marajoensis, Bothrops matogrossensis, Bothrops moojeni, Bothrops neuwiedi, Bothrops pauloensis, Bothrops pirajai, Bothrops pradoi, Bothrops pubescens, Bothrops taeniatus, Crotalus adamanteus, Crotalus durissus, Crotalus durissus cumanensis, Lachesis muta, Micrurus frontalis, no activity in Loxosceles gaucho, no activity in Philodryas olfersii
Comp. Biochem. Physiol. C
147C
85-95
2008
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26
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692192
Pedrazza
Ecto-nucleotidase pathway is a ...
Rattus norvegicus, Rattus norvegicus Wistar
Eur. J. Pharmacol.
583
18-25
2008
2
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167
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694864
Frederick
A role for a lithium-inhibited ...
Mus musculus
Proc. Natl. Acad. Sci. USA
105
11605-11612
2008
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2
2
1
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2
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15
3
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15
3
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1
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729916
Zhou
Proteasomal components require ...
Haloferax volcanii, Haloferax volcanii DS2
J. Bacteriol.
190
8096-8105
2008
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2
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1
1
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665044
Devader
Xenopus apyrase (xapy), a secr ...
Xenopus laevis
Gene
367
135-141
2006
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1
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6
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4
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680687
Yang
Calcium-dependent dimerization ...
Homo sapiens
J. Biol. Chem.
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28307-28317
2006
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1
1
8
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3
2
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8
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2
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1
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1
1
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681602
Yegutkin
Intravascular ADP and soluble ...
Homo sapiens
J. Physiol.
579
553-564
2006
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656266
Proudfoot
General Enzymatic Screens Iden ...
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54687-54694
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12
18
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6
5
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1
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2
1
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18
3
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4
18
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6
5
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1
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15
2
1
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18
3
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664646
Borges
-
Nucleotidase activities in mem ...
Helix aspersa
Comp. Biochem. Physiol. B
137B
297-307
2004
3
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4
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8
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654871
Passariello
The molecular class C acid pho ...
Elizabethkingia meningoseptica
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203-209
2003
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1
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10
10
1
2
2
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1
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10
1
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10
1
1
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9
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1
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1
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9
10
-
10
1
2
2
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1
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1
-
10
1
-
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10
1
1
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656785
Vance
Repair of DNA strand breaks by ...
Saccharomyces cerevisiae
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1
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2
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654913
Tikhaya
-
Biochemical adaptation of barl ...
Hordeum vulgare
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1
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655137
Nikbakht
Complex hippocampal responses ...
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1
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81060
Hoglund
Cytoplasmic 5'(3')-nucleotidas ...
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1
1
12
1
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1
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3
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1
12
1
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95065
Skladanowski
Partial purification and prope ...
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81057
Yokoyama
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Purification and characterizat ...
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-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
1
-
1
1
-
10
-
-
-
1
-
1
2
-
-
-
-
-
-
-
-
81058
Hokari
Rat spleen cytoplasmic nucleot ...
Rattus norvegicus
Int. J. Biochem.
20
1405-1410
1988
-
-
-
-
-
-
-
8
2
-
1
1
-
3
-
-
1
-
-
7
-
-
19
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
8
2
-
1
1
-
-
-
1
-
7
-
-
19
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
81059
Haugen
Cellular localization and deve ...
Rattus norvegicus
Int. J. Biochem.
19
193-196
1987
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
8
-
-
9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
8
-
-
9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81061
Tjernshaugen
Activity of deoxyinosine-activ ...
Homo sapiens, Oryctolagus cuniculus, Rattus norvegicus
Int. J. Biochem.
13
417-421
1981
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
18
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
18
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81063
Simonis
Studies on a membrane-bound nu ...
uncultured marine bacterium
Int. J. Biochem.
13
733-738
1981
-
-
-
-
-
-
-
23
1
3
-
-
-
2
-
-
-
-
-
-
-
-
22
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
23
1
3
-
-
-
-
-
-
-
-
-
-
22
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81062
Tjershaugen
-
Deoxyadenosine-activated nucle ...
Rattus norvegicus
Acta Chem. Scand. B
33
384-390
1979
5
-
-
-
-
-
-
2
-
-
1
-
-
1
-
-
1
-
-
1
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
1
-
1
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
81064
Delaunay
Properties of a non-specific n ...
Oryctolagus cuniculus
Biochim. Biophys. Acta
527
425-431
1978
-
-
-
-
-
-
2
5
2
2
-
-
-
2
-
-
-
-
-
1
1
-
15
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
5
2
2
-
-
-
-
-
-
-
1
1
-
15
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
81065
Arsenis
An acid nucleotidase from rat ...
Rattus norvegicus
Methods Enzymol.
51
271-275
1978
-
-
-
-
-
-
8
3
2
-
-
-
-
2
-
-
1
-
-
2
1
-
6
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
8
-
3
2
-
-
-
-
-
-
1
-
2
1
-
6
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
81066
Tjernshaugen
Partial purification and prope ...
Rattus norvegicus
Biochem. J.
169
597-605
1978
-
-
-
-
-
-
3
15
1
-
1
-
-
2
-
-
1
-
-
2
1
1
32
-
-
-
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
15
1
-
1
-
-
-
-
1
-
2
1
1
32
-
-
-
1
-
2
-
-
-
-
-
-
-
-
-
81067
Schrader
Membrane-bound nucleotidase of ...
Bacillus cereus
J. Bacteriol.
133
576-583
1978
-
-
-
-
-
-
-
-
1
1
1
-
-
3
-
-
1
-
-
-
1
-
15
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
1
-
-
-
-
1
-
-
1
-
15
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
81068
Tjernshaugen
Subcellular distribution and a ...
Rattus norvegicus
Biochem. J.
154
77-80
1976
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
16
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
16
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81069
Fritzson
Kinetic analysis of a rat-live ...
Rattus norvegicus
Eur. J. Biochem.
38
408-415
1973
11
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
11
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81070
Fritzson
Regulation of rat-liver nucleo ...
Rattus norvegicus
Eur. J. Biochem.
27
38-42
1972
3
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81071
Fritzson
A new nucleotidase of rat live ...
Rattus norvegicus
Biochim. Biophys. Acta
235
128-141
1971
-
-
-
-
-
1
-
7
1
-
1
-
-
2
-
-
1
-
-
2
2
1
9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
7
1
-
1
-
-
-
-
1
-
2
2
1
9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
81072
Arsenis
Purification and properties of ...
Rattus norvegicus
J. Biol. Chem.
243
5702-5708
1968
-
-
-
-
-
-
3
-
2
1
1
-
-
2
-
-
1
-
-
2
1
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
2
1
1
-
-
-
-
1
-
2
1
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-