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Literature summary for 3.1.3.27 extracted from
- The pgpA and pgpB genes of Escherichia coli are not essential: evidence for a third phosphatidylglycerophosphate phosphatase (1992), J. Bacteriol., 174, 205-213.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | 1 mM | Escherichia coli |  |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| Escherichia coli strains lacking the original pgpA and/or pgpB genes | Escherichia coli |
General Stability
| General Stability | Organism |
|---|---|
| heat labile | Escherichia coli |
| PGP-C more sensitive to increasing temperature | Escherichia coli |
| sensitive to sulfhydryl reagents and freeze-thaw cycles | Escherichia coli |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| HgCl2 | - |
Escherichia coli | |
| NaF | - |
Escherichia coli | |
| phosphate | - |
Escherichia coli | |
| Triton X-100 | only in heat treatment | Escherichia coli | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| inner membrane | - |
Escherichia coli | - |
- |
| membrane | - |
Escherichia coli | 16020 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | 4 mM, not required for PGPB-tase | Escherichia coli | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phosphatidylglycerophosphate + H2O | Escherichia coli | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 5.2 | - |
PGPC-tase | Escherichia coli |
| 6 | - |
PGPA-tase, more specific for phosphatidylglycerolphosphate than PGPB-tase | Escherichia coli |
| 10.1 | - |
PGPB-tase | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phosphatidylglycerophosphate + H2O | - |
Escherichia coli | phosphatidylglycerol + phosphate | - |
? | |
| phosphatidylglycerophosphate + H2O | - |
Escherichia coli | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PGP-tase | - |
Escherichia coli |
| PGPA-tase | - |
Escherichia coli |
| PGPB-tase | - |
Escherichia coli |
| PGPC-tase | - |
Escherichia coli |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 7.5 | - |
Escherichia coli |
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