Any feedback?
Literature summary for 3.1.3.25 extracted from
- myo-inositol monophosphatase: a challenging target for mood stabilising drugs (2007), Mini Rev. Med. Chem., 7, 107-113.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| (1R,2R,4R,6R)-2,4-dihydroxy-6-[4-(2-hydroxyphenyl)butoxy]cyclohexyl phosphate | - |
Homo sapiens |  |
| (1S,2R,4S,6R)-6-(butylamino)cyclohexane-1,2,4-triol | - |
Homo sapiens | |
| (phenylmethanediyl)bis(phosphonic acid) | - |
Homo sapiens | |
| 1-(4-hydroxyphenyloxy)ethane-1,1-bisphosphonic acid | - |
Homo sapiens | |
| 2,3,7-trihydroxycyclohepta-2,4,6-trien-1-one | - |
Homo sapiens | |
| Li+ | - |
Homo sapiens | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | cofactor requirement for 3 Mg2+ ions | Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 60000 | - |
SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alpha-D-galactose 1-phosphate + H2O | - |
Homo sapiens | alpha-D-galactose + phosphate | - |
? | |
| D-erythrose 4-phosphate + H2O | - |
Homo sapiens | D-erythrose + phosphate | - |
? | |
| D-fructose 1,6-bisphosphate + H2O | - |
Homo sapiens | D-fructose 6-phosphate + phosphate | - |
? | |
| D-fructose 1-phosphate + H2O | - |
Homo sapiens | D-fructose + phosphate | - |
? | |
| D-fructose 6-phosphate + H2O | - |
Homo sapiens | D-fructose + phosphate | - |
? | |
| D-glucose 6-phosphate + H2O | - |
Homo sapiens | D-glucose + phosphate | - |
? | |
| D-myo-inositol 1-phosphate + H2O | - |
Homo sapiens | D-myo-inositol + phosphate | - |
? | |
| D-ribose 5-phosphate + H2O | - |
Homo sapiens | D-ribose + phosphate | - |
? | |
| D-xylose 5-phosphate + H2O | - |
Homo sapiens | D-xylose + phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homodimer | - |
Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| IMPase | - |
Homo sapiens |
| myo-inositol monophosphatase | - |
Homo sapiens |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.3 | - |
(1S,2R,4S,6R)-6-(butylamino)cyclohexane-1,2,4-triol | - |
Homo sapiens | |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.00007 | - |
- |
Homo sapiens | (1R,2R,4R,6R)-2,4-dihydroxy-6-[4-(2-hydroxyphenyl)butoxy]cyclohexyl phosphate | |
| 0.0002 | - |
- |
Homo sapiens | 1-(4-hydroxyphenyloxy)ethane-1,1-bisphosphonic acid | |
| 0.0002 | - |
- |
Homo sapiens | (phenylmethanediyl)bis(phosphonic acid) | |
| 0.0008 | - |
- |
Homo sapiens | 2,3,7-trihydroxycyclohepta-2,4,6-trien-1-one | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
