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Literature summary for 3.1.3.2 extracted from

  • Felts, R.L.; Reilly, T.J.; Tanner, J.J.
    Structure of Francisella tularensis AcpA: prototype of a unique superfamily of acid phosphatases and phospholipases C (2006), J. Biol. Chem., 281, 30289-30298.
    View publication on PubMed
Search for more literature for 3.1.3.2

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Francisella tularensis

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with orthovanadate, using polyethylene glycol 1500 as the precipitating agent Francisella tularensis

Protein Variants

Protein Variants Comment Organism
S175A no detectable activity Francisella tularensis

Inhibitors

Inhibitors Comment Organism Structure
orthovanadate competitive inhibitor Francisella tularensis

Organism

Organism UniProt Comment Textmining
Francisella tularensis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Francisella tularensis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-ribose 5-phosphate + H2O
-
 Francisella tularensis D-ribose + phosphate
-
 ?
NADP+ + H2O
-
 Francisella tularensis NAD+ + phosphate
-
 ?
p-nitrophenyl phosphate + H2O
-
 Francisella tularensis p-nitrophenol + phosphate
-
 ?
p-nitrophenyl phosphorylcholine + H2O
-
 Francisella tularensis p-nitrophenol + phosphorylcholine
-
 ?

Subunits

Subunits Comment Organism
dimer ultracentrifugation and gel filtration Francisella tularensis

Synonyms

Synonyms Comment Organism
acid phosphatase A
-
 Francisella tularensis
AcpA
-
 Francisella tularensis