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Literature summary for 3.1.3.17 extracted from

  • Browne, G.J.; Delibegovic, M.; Keppens, S.; Stalmans, W.; Cohen, P.T.W.
    The level of the glycogen targeting regulatory subunit R5 of protein phosphatase 1 is decreased in the livers of insulin-dependent diabetic rats and starved rats (2001), Biochem. J., 360, 449-459.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.3.17

Activating Compound

Activating Compound Comment Organism Structure
Insulin induces the enzyme in diabetic rats Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
additional information withholding food decreases the enzyme activity in rats Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information the enzyme is glycogen-bound via a glycogen-targeting subunit Rattus norvegicus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
additional information no bivalent metal ions required Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus subunit interaction, role in controle and regulation, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male Wistar rats
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Rattus norvegicus
0.000053
-
 liver lysate Rattus norvegicus
0.00422
-
 glycogen fraction Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glycogen phosphorylase + H2O
-
 Rattus norvegicus ?
-
 ?
additional information subunit interaction, role in controle and regulation, overview Rattus norvegicus ?
-
 ?

Subunits

Subunits Comment Organism
More subunit interaction, role in controle and regulation, overview Rattus norvegicus

Synonyms

Synonyms Comment Organism
PP1
-
 Rattus norvegicus
protein phosphatase 1
-
 Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Rattus norvegicus