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Literature summary for 3.1.3.16 extracted from

  • Taira, J.; Kida, Y.; Kuwano, K.; Higashimoto, Y.
    Protein phosphatase 2A dephosphorylates phosphoserines in nucleocytoplasmic shuttling and secretion of high mobility group box 1 (2013), J. Biochem., 154, 299-308.
    View publication on PubMed
Search for more literature for 3.1.3.16

Inhibitors

Inhibitors Comment Organism Structure
endothall
-
 Mus musculus
additional information not inhibited by NIPP-1 Mus musculus
okadaic acid
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Mus musculus 5737
-
nucleus
-
 Mus musculus 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35000
-
 x * 35000, catalytic subunit, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphorylated High mobility group box 1 protein + H2O Mus musculus
-
 High mobility group box 1 protein + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
RAW-264.7 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphorylated High mobility group box 1 protein + H2O
-
 Mus musculus High mobility group box 1 protein + phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 35000, catalytic subunit, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
PP2A
-
 Mus musculus
protein phosphatase 2A
-
 Mus musculus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00009
-
 in 50 mM Tris-HCl (pH 7.4), temperature not specified in the publication Mus musculus endothall