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Literature summary for 3.1.3.16 extracted from

  • Oxenrider, K.A.; Kennelly, P.J.
    A protein-serine phosphatase from the halophilic archaeon Haloferax volcanii (1993), Biochem. Biophys. Res. Commun., 194, 1330-1335.
    View publication on PubMed
Search for more literature for 3.1.3.16

Inhibitors

Inhibitors Comment Organism Structure
4-nitrophenyl phosphate 10 mM, 89% inhibition Haloferax volcanii
diethylpyrocarbonate
-
 Haloferax volcanii
diphosphate 10 mM, complete inhibition Haloferax volcanii
molybdate 1 mM, 70% inhibition Haloferax volcanii
additional information activity is unaffected by other potential inhibitors or activators such as polyamines, heparin, cyclic nucleotides, Ca2+/calmodulin, tartrate, tetramisole, okadaic acid, microcystin LR, or sulfhydryl-modifying agents Haloferax volcanii
NaF 50 mM, 47% inhibition Haloferax volcanii
phosphate 50 mM, complete inhibition Haloferax volcanii
vanadate 1 mM, complete inhibition Haloferax volcanii
Zn2+ 5 mM, complete inhibition Haloferax volcanii

Metals/Ions

Metals/Ions Comment Organism Structure
Cd2+ 20 mM, stimulation is about 45% compared to that with Mn2+ Haloferax volcanii
Co2+ 20 mM, stimulation is about 15% compared to that with Mn2+ Haloferax volcanii
Mn2+ 20 mM, stimulates Haloferax volcanii
Ni2+ 20 mM, stimulation is about 5% compared to that with Mn2+ Haloferax volcanii

Organism

Organism UniProt Comment Textmining
Haloferax volcanii
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[protein]-L-serine phosphate + H2O the enzyme dephosphorylates phosphoseryl residues in casein, mixed histones, and phosphorylase a, but not phosphotyrosyl residues in reduced, carboxyamidomethylated and maleylated lysozyme Haloferax volcanii [protein]-L-serine + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
protein-serine phosphatase
-
 Haloferax volcanii