Activating Compound | Comment | Organism | Structure |
---|---|---|---|
estrogen | estrogen maintains the function of isozymes PP1, PP2A, and calcineurin | Rattus norvegicus | |
estrogen | estrogen maintains the function of PP1, PP2A, and calcineurin | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cyclosporin A | specific inhibitor of calcineurin | Homo sapiens | |
cyclosporin A | specific inhibitor of calcineurin | Rattus norvegicus | |
endothall | specific inhibitor of isozyme PP2A | Homo sapiens | |
endothall | specific inhibitor of isozyme PP2A | Rattus norvegicus | |
glutamate | inhibitor of isozyme PP2A | Homo sapiens | |
glutamate | inhibitor of isozyme PP2A | Rattus norvegicus | |
additional information | protein phosphatase inhibitor II and cyclosporin A have no inhibitory effect on isozyme PP2A | Homo sapiens | |
additional information | protein phosphatase inhibitor II and cyclosporin A have no inhibitory effect on isozyme PP2A | Rattus norvegicus | |
okadaic acid | inhibitor of isozyme PP2A | Homo sapiens | |
okadaic acid | inhibitor of isozyme PP2A | Rattus norvegicus | |
protein phosphatase inhibitor II | specific inhibitor of isozyme PP1 | Homo sapiens | |
protein phosphatase inhibitor II | specific inhibitor of isozyme PP1 | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
isozyme PP1, SDS-PAGE | Homo sapiens |
32000 | - |
isozyme PP2A, SDS-PAGE | Homo sapiens |
60000 | - |
isozyme PP2B, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
C6 glioma cell | - |
Rattus norvegicus | - |
cerebral cortical neuron | - |
Rattus norvegicus | - |
glioma cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phospho-threonylpeptide + H2O | - |
Homo sapiens | threonylpeptide + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
calcineurin | - |
Homo sapiens |
calcineurin | - |
Rattus norvegicus |
PP1 | - |
Homo sapiens |
PP1 | - |
Rattus norvegicus |
PP2A | - |
Homo sapiens |
PP2A | - |
Rattus norvegicus |
PP2B | - |
Homo sapiens |
PP2B | - |
Rattus norvegicus |
protein phosphatase 1 | - |
Homo sapiens |
protein phosphatase 1 | - |
Rattus norvegicus |
protein phosphatase 2A | - |
Homo sapiens |
protein phosphatase 2A | - |
Rattus norvegicus |
protein phosphatase 2B | - |
Homo sapiens |
protein phosphatase 2B | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
Calmodulin | - |
Homo sapiens | |
Calmodulin | - |
Rattus norvegicus |