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Literature summary for 3.1.3.11 extracted from

  • De Porcellinis, A.J.; Noergaard, H.; Brey, L.M.F.; Erstad, S.M.; Jones, P.R.; Heazlewood, J.L.; Sakuragi, Y.
    Overexpression of bifunctional fructose-1,6-bisphosphatase/sedoheptulose-1,7-bisphosphatase leads to enhanced photosynthesis and global reprogramming of carbon metabolism in Synechococcus sp. PCC 7002 (2018), Metab. Eng., 47, 170-183 .
    View publication on PubMed
Search for more literature for 3.1.3.11

Cloned(Commentary)

Cloned (Comment) Organism
gene SYNPCC7002_A1301, recombinant overexpression in Synechocystis sp. PCC 7002 cells Synechococcus sp. PCC 7002

Protein Variants

Protein Variants Comment Organism
additional information overexpression of bifunctional fructose-1,6-bisphosphatase/sedoheptulose-1,7-bisphosphatase (BiBPase) alters the carbon partitioning to extracellular carbohydrate. It induces carbohydrate partitioning which is significantly different from that in the wild-type and more towards extracellular carbohydrate and less towards glycogen. The activities of aldolase and ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) are enhanced by overexpression of BiBPase compared to wild-type, while glucose 6-phosphate dehydrogenase activity is decreased. Overexpression of BiBPase leads to enhanced cell size and photosynthetic O2 evolution. Overexpression of BiBPase in Synechococcus sp. PCC 7002 confers faster growth under elevated [CO2] and light conditions, but not under conditions where the amount of either light or CO2 is limiting Synechococcus sp. PCC 7002

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-fructose 1,6-bisphosphate + H2O Synechococcus sp. PCC 7002
-
 D-fructose 6-phosphate + phosphate
-
 ?
D-fructose 1,6-bisphosphate + H2O Synechococcus sp. PCC 7002 ATCC 27264
-
 D-fructose 6-phosphate + phosphate
-
 ?
D-fructose 1,6-bisphosphate + H2O Synechococcus sp. PCC 7002 PR-6
-
 D-fructose 6-phosphate + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Synechococcus sp. B1XLK5 bifunctional D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase, EC 3.1.3.11 and EC 3.1.3.37, respectively
-
Synechococcus sp. PCC 7002 B1XLK5
-
-
Synechococcus sp. PCC 7002 B1XLK5 i.e. Synechocystis sp. PCC 7002
-
Synechococcus sp. PCC 7002 ATCC 27264 B1XLK5 i.e. Synechocystis sp. PCC 7002
-
Synechococcus sp. PCC 7002 PR-6 B1XLK5 i.e. Synechocystis sp. PCC 7002
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-fructose 1,6-bisphosphate + H2O
-
 Synechococcus sp. PCC 7002 D-fructose 6-phosphate + phosphate
-
 ?
D-fructose 1,6-bisphosphate + H2O
-
 Synechococcus sp. PCC 7002 ATCC 27264 D-fructose 6-phosphate + phosphate
-
 ?
D-fructose 1,6-bisphosphate + H2O
-
 Synechococcus sp. PCC 7002 PR-6 D-fructose 6-phosphate + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
BiBPase
-
 Synechococcus sp. PCC 7002
BiBPase
-
 Synechococcus sp.
bifunctional fructose-1,6-bisphosphatase/sedoheptulose-1,7-bisphosphatase
-
 Synechococcus sp. PCC 7002
fructose-1,6-bisphosphatase/sedoheptulose-1,7-bisphosphatase
-
 Synechococcus sp. PCC 7002
More cf. Ec 3.1.3.37 Synechococcus sp. PCC 7002
SYNPCC7002_A1301
-
 Synechococcus sp. PCC 7002
SYNPCC7002_A1301
-
 Synechococcus sp.

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Synechococcus sp. PCC 7002

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Synechococcus sp. PCC 7002

General Information

General Information Comment Organism
malfunction overexpression of bifunctional fructose-1,6-bisphosphatase/sedoheptulose-1,7-bisphosphatase (BiBPase) alters the carbon partitioning to extracellular carbohydrate. It induces carbohydrate partitioning which is significantly different from that in the wild-type and more towards extracellular carbohydrate and less towards glycogen. The activities of aldolase and ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) are enhanced by overexpression of BiBPase compared to wild-type, while glucose 6-phosphate dehydrogenase activity is decreased. Overexpression of BiBPase leads to enhanced cell size and photosynthetic O2 evolution. Overexpression of BiBPase in Synechococcus sp. PCC 7002 confers faster growth under elevated [CO2] and light conditions, but not under conditions where the amount of either light or CO2 is limiting Synechococcus sp. PCC 7002
metabolism overexpression of bifunctional fructose-1,6-bisphosphatase/sedoheptulose-1,7-bisphosphatase leads to enhanced photosynthesis and global reprogramming of carbon metabolism Synechococcus sp. PCC 7002
physiological function overexpression of BiBPase enhances growth, cell size, and photosynthetic O2 evolution, and coordinately upregulates enzymes in the Calvin Benson cycle including RuBisCO and fructose-1,6-bisphosphate aldolase. Overexpression downregulates enzymes in respiratory carbon metabolism including glucose-6-phosphate dehydrogenase. The content of glycogen is significantly reduced while the soluble carbohydrate content is increased Synechococcus sp.