Literature summary for 3.1.3.11 extracted from

Yanez, A.J.; Bustamante, X.; Bertinat, R.; Werner, E.; Rauch, M.C.; Concha, I.I.; Reyes, J.G.; Slebe, J.C.
Expression of key substrate cycle enzymes in rat spermatogenic cells: fructose 1,6 bisphosphatase and 6 phosphofructose 1-kinase (2007), J. Cell. Physiol., 212, 807-816.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-fructose 1,6-bisphosphate + H2O	Rattus norvegicus	the coregulation of phosphofructo 1-kinase I and fructose 1,6-bisphosphatase are required for the ability of these cells to respond to glucose and induce metabolic and Ca2+ signals that can be important for sperm development and function	D-fructose 6-phosphate + phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
Sertoli cell	-	Rattus norvegicus	-
spermatocyte	expression of FBPase at the mRNA and protein levels is stronger in round and elongating spermatids as compared to other spermatogenic cells	Rattus norvegicus	-
testis	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-fructose 1,6-bisphosphate + H2O	the coregulation of phosphofructo 1-kinase I and fructose 1,6-bisphosphatase are required for the ability of these cells to respond to glucose and induce metabolic and Ca2+ signals that can be important for sperm development and function	Rattus norvegicus	D-fructose 6-phosphate + phosphate	-	?

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Release 2023.1 (January 2023)