BRENDA - Enzyme Database
show all sequences of 3.1.3.103

Human symbiont Bacteroides thetaiotaomicron synthesizes 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN)

Wang, L.; Lu, Z.; Allen, K.; Mariano, P.; Dunaway-Mariano, D.; Chem. Biol. 15, 893-897 (2008)

Data extracted from this reference:

KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.11
-
3-deoxy-D-glycero-D-galacto-nononate 9-phosphate
pH 7, 25°C
Bacteroides thetaiotaomicron
0.12
-
N-acetylneuraminic acid 9-phosphate
pH 7, 25°C
Bacteroides thetaiotaomicron
0.31
-
2-dehydro-3-deoxy-D-manno-octulosonic acid 8-phosphate
pH 7, 25°C
Bacteroides thetaiotaomicron
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3-deoxy-D-glycero-D-galacto-nononate 9-phosphate + H2O
Bacteroides thetaiotaomicron
-
3-deoxy-D-glycero-D-galacto-nononate + phosphate
-
-
?
3-deoxy-D-glycero-D-galacto-nononate 9-phosphate + H2O
Bacteroides thetaiotaomicron DSM 2079
-
3-deoxy-D-glycero-D-galacto-nononate + phosphate
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Bacteroides thetaiotaomicron
Q8A712
-
-
Bacteroides thetaiotaomicron DSM 2079
Q8A712
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-dehydro-3-deoxy-D-manno-octulosonic acid 8-phosphate + H2O
-
738039
Bacteroides thetaiotaomicron
2-dehydro-3-deoxy-D-manno-octulosonic acid + phosphate
-
-
-
?
2-dehydro-3-deoxy-D-manno-octulosonic acid 8-phosphate + H2O
-
738039
Bacteroides thetaiotaomicron DSM 2079
2-dehydro-3-deoxy-D-manno-octulosonic acid + phosphate
-
-
-
?
3-deoxy-D-glycero-D-galacto-nononate 9-phosphate + H2O
-
738039
Bacteroides thetaiotaomicron
3-deoxy-D-glycero-D-galacto-nononate + phosphate
-
-
-
?
3-deoxy-D-glycero-D-galacto-nononate 9-phosphate + H2O
-
738039
Bacteroides thetaiotaomicron DSM 2079
3-deoxy-D-glycero-D-galacto-nononate + phosphate
-
-
-
?
N-acetylneuraminic acid 9-phosphate + H2O
-
738039
Bacteroides thetaiotaomicron
N-acetylneuraminic acid + phosphate
-
-
-
?
N-acetylneuraminic acid 9-phosphate + H2O
-
738039
Bacteroides thetaiotaomicron DSM 2079
N-acetylneuraminic acid + phosphate
-
-
-
?
Turnover Number [1/s]
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
0.06
-
2-dehydro-3-deoxy-D-manno-octulosonic acid 8-phosphate
pH 7, 25°C
Bacteroides thetaiotaomicron
0.73
-
N-acetylneuraminic acid 9-phosphate
pH 7, 25°C
Bacteroides thetaiotaomicron
1.2
-
3-deoxy-D-glycero-D-galacto-nononate 9-phosphate
pH 7, 25°C
Bacteroides thetaiotaomicron
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.11
-
3-deoxy-D-glycero-D-galacto-nononate 9-phosphate
pH 7, 25°C
Bacteroides thetaiotaomicron
0.12
-
N-acetylneuraminic acid 9-phosphate
pH 7, 25°C
Bacteroides thetaiotaomicron
0.31
-
2-dehydro-3-deoxy-D-manno-octulosonic acid 8-phosphate
pH 7, 25°C
Bacteroides thetaiotaomicron
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3-deoxy-D-glycero-D-galacto-nononate 9-phosphate + H2O
Bacteroides thetaiotaomicron
-
3-deoxy-D-glycero-D-galacto-nononate + phosphate
-
-
?
3-deoxy-D-glycero-D-galacto-nononate 9-phosphate + H2O
Bacteroides thetaiotaomicron DSM 2079
-
3-deoxy-D-glycero-D-galacto-nononate + phosphate
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-dehydro-3-deoxy-D-manno-octulosonic acid 8-phosphate + H2O
-
738039
Bacteroides thetaiotaomicron
2-dehydro-3-deoxy-D-manno-octulosonic acid + phosphate
-
-
-
?
2-dehydro-3-deoxy-D-manno-octulosonic acid 8-phosphate + H2O
-
738039
Bacteroides thetaiotaomicron DSM 2079
2-dehydro-3-deoxy-D-manno-octulosonic acid + phosphate
-
-
-
?
3-deoxy-D-glycero-D-galacto-nononate 9-phosphate + H2O
-
738039
Bacteroides thetaiotaomicron
3-deoxy-D-glycero-D-galacto-nononate + phosphate
-
-
-
?
3-deoxy-D-glycero-D-galacto-nononate 9-phosphate + H2O
-
738039
Bacteroides thetaiotaomicron DSM 2079
3-deoxy-D-glycero-D-galacto-nononate + phosphate
-
-
-
?
N-acetylneuraminic acid 9-phosphate + H2O
-
738039
Bacteroides thetaiotaomicron
N-acetylneuraminic acid + phosphate
-
-
-
?
N-acetylneuraminic acid 9-phosphate + H2O
-
738039
Bacteroides thetaiotaomicron DSM 2079
N-acetylneuraminic acid + phosphate
-
-
-
?
Turnover Number [1/s] (protein specific)
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
0.06
-
2-dehydro-3-deoxy-D-manno-octulosonic acid 8-phosphate
pH 7, 25°C
Bacteroides thetaiotaomicron
0.73
-
N-acetylneuraminic acid 9-phosphate
pH 7, 25°C
Bacteroides thetaiotaomicron
1.2
-
3-deoxy-D-glycero-D-galacto-nononate 9-phosphate
pH 7, 25°C
Bacteroides thetaiotaomicron
General Information
General Information
Commentary
Organism
physiological function
enzyme belongs to a biosynthetic pathway that forms and cytidylates 2-dehydro-3-deoxy-D-glycero-D-galacto-nononic acid
Bacteroides thetaiotaomicron
General Information (protein specific)
General Information
Commentary
Organism
physiological function
enzyme belongs to a biosynthetic pathway that forms and cytidylates 2-dehydro-3-deoxy-D-glycero-D-galacto-nononic acid
Bacteroides thetaiotaomicron
Other publictions for EC 3.1.3.103
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
738574
Lu
Structure-function analysis of ...
Bacteroides thetaiotaomicron, Bacteroides thetaiotaomicron DSM 2079
J. Biol. Chem.
284
1224-1233
2009
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4
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4
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4
4
738039
Wang
Human symbiont Bacteroides the ...
Bacteroides thetaiotaomicron, Bacteroides thetaiotaomicron DSM 2079
Chem. Biol.
15
893-897
2008
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3
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3
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3
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6
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3
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1
1
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