Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,5-dimethoxy-N-(pyridin-3-yl)benzene-1-sulfonamide | - |
Mus musculus | |
2-cyano-6-methoxy-N-(pyridin-3-yl)benzene-1-sulfonamide | - |
Mus musculus | |
2-methoxy-5-methyl-N-(pyridin-3-yl)benzene-1-sulfonamide | - |
Mus musculus | |
3-methoxy-2-[(pyridin-3-yl)sulfamoyl]benzamide | - |
Mus musculus | |
3-methoxy-N-(pyridin-3-yl)[1,1'-biphenyl]-2-sulfonamide | - |
Mus musculus | |
5-((5-chloro-2-methoxyphenyl)sulfonamido)nicotinamide | SBI-425, potent inhibitor | Mus musculus | |
5-chloro-2-methoxy-N-(pyridin-3-yl)benzene-1-sulfonamide | - |
Mus musculus | |
5-chloro-2-methoxy-N-[5-(2-methylphenyl)pyridin-3-yl]benzene-1-sulfonamide | - |
Mus musculus | |
5-chloro-2-methoxy-N-[5-(3-methylphenyl)pyridin-3-yl]benzene-1-sulfonamide | - |
Mus musculus | |
5-chloro-2-methoxy-N-[5-(4-methoxyphenyl)pyridin-3-yl]benzene-1-sulfonamide | - |
Mus musculus | |
5-chloro-2-methoxy-N-[5-(4-methylphenyl)pyridin-3-yl]benzene-1-sulfonamide | - |
Mus musculus | |
5-chloro-2-methoxy-N-[5-(4-methylpiperazine-1-carbonyl)pyridin-3-yl]benzene-1-sulfonamide | - |
Mus musculus | |
5-chloro-N-[5-(4-chlorophenyl)pyridin-3-yl]-2-methoxybenzene-1-sulfonamide | - |
Mus musculus | |
5-methyl-3-[3-[3-(trifluoromethyl)phenyl]prop-2-yn-1-yl]oxolan-2-one | - |
Mus musculus | |
5-[(5-bromo-2-methoxybenzene-1-sulfonyl)amino]pyridine-3-carboxamide | - |
Mus musculus | |
5-[(5-chloro-2-methoxybenzene-1-sulfonyl)amino]-N-ethylpyridine-3-carboxamide | - |
Mus musculus | |
5-[(5-chloro-2-methoxybenzene-1-sulfonyl)amino]-N-methylpyridine-3-carboxamide | - |
Mus musculus | |
5-[(5-chloro-2-methoxybenzene-1-sulfonyl)amino]-N-phenylpyridine-3-carboxamide | - |
Mus musculus | |
5-[(5-chloro-2-methoxybenzene-1-sulfonyl)amino]pyridine-3-carboxamide | SBI-425, potent inhibitor | Mus musculus | |
5-[(5-chloro-2-methoxybenzene-1-sulfonyl)amino]pyridine-3-carboxylic acid | - |
Mus musculus | |
5-[(5-fluoro-2-methoxybenzene-1-sulfonyl)amino]pyridine-3-carboxamide | - |
Mus musculus | |
5-[[2-methoxy-5-(trifluoromethoxy)benzene-1-sulfonyl]amino]pyridine-3-carboxamide | - |
Mus musculus | |
5-[[5-chloro-2-(trifluoromethoxy)benzene-1-sulfonyl]amino]pyridine-3-carboxamide | - |
Mus musculus | |
6-(1-benzofuran-2-yl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole | - |
Mus musculus | |
6-(5-nitro-1-benzothiophen-2-yl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole | - |
Mus musculus | |
6-(thiophen-3-yl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole | - |
Mus musculus | |
levamisole | - |
Mus musculus | |
methyl 3-methoxy-2-[(pyridin-3-yl)sulfamoyl]benzoate | - |
Mus musculus | |
methyl 5-[(5-chloro-2-methoxybenzene-1-sulfonyl)amino]pyridine-3-carboxylate | - |
Mus musculus | |
MLS-0038949 | - |
Mus musculus | |
N-(2-hydroxyethyl)-3-(2,3,4-trichlorophenyl)-1H-pyrazole-5-carboxamide | - |
Mus musculus | |
N-([3,3'-bipyridin]-5-yl)-2,5-dimethoxybenzene-1-sulfonamide | - |
Mus musculus | |
N-([3,3'-bipyridin]-5-yl)-5-chloro-2-methoxybenzene-1-sulfonamide | - |
Mus musculus | |
N-([3,4'-bipyridin]-5-yl)-2,5-dimethoxybenzene-1-sulfonamide | - |
Mus musculus | |
N-([3,4'-bipyridin]-5-yl)-5-chloro-2-methoxybenzene-1-sulfonamide | - |
Mus musculus | |
theophylline | - |
Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P09242 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood plasma | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
tissue-nonspecific alkaline phosphatase | - |
Mus musculus |
TNAP | - |
Mus musculus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000014 | - |
pH and temperature not specified in the publication | Mus musculus | 5-[(5-bromo-2-methoxybenzene-1-sulfonyl)amino]pyridine-3-carboxamide | |
0.000016 | - |
pH and temperature not specified in the publication | Mus musculus | 5-[(5-chloro-2-methoxybenzene-1-sulfonyl)amino]pyridine-3-carboxamide | |
0.000019 | - |
pH and temperature not specified in the publication | Mus musculus | 5-[(5-fluoro-2-methoxybenzene-1-sulfonyl)amino]pyridine-3-carboxamide | |
0.000023 | - |
pH and temperature not specified in the publication | Mus musculus | 5-chloro-2-methoxy-N-[5-(4-methoxyphenyl)pyridin-3-yl]benzene-1-sulfonamide | |
0.000026 | - |
pH and temperature not specified in the publication | Mus musculus | N-(2-hydroxyethyl)-3-(2,3,4-trichlorophenyl)-1H-pyrazole-5-carboxamide | |
0.000038 | - |
pH and temperature not specified in the publication | Mus musculus | 6-(thiophen-3-yl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole | |
0.000043 | - |
pH and temperature not specified in the publication | Mus musculus | 6-(5-nitro-1-benzothiophen-2-yl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole | |
0.000065 | - |
pH and temperature not specified in the publication | Mus musculus | methyl 5-[(5-chloro-2-methoxybenzene-1-sulfonyl)amino]pyridine-3-carboxylate | |
0.000073 | - |
pH and temperature not specified in the publication | Mus musculus | N-([3,3'-bipyridin]-5-yl)-5-chloro-2-methoxybenzene-1-sulfonamide | |
0.000073 | - |
pH and temperature not specified in the publication | Mus musculus | N-([3,4'-bipyridin]-5-yl)-2,5-dimethoxybenzene-1-sulfonamide | |
0.000073 | - |
pH and temperature not specified in the publication | Mus musculus | N-([3,4'-bipyridin]-5-yl)-5-chloro-2-methoxybenzene-1-sulfonamide | |
0.000084 | - |
pH and temperature not specified in the publication | Mus musculus | 6-(1-benzofuran-2-yl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole | |
0.000109 | - |
pH and temperature not specified in the publication | Mus musculus | 5-[(5-chloro-2-methoxybenzene-1-sulfonyl)amino]-N-methylpyridine-3-carboxamide | |
0.00012 | - |
pH and temperature not specified in the publication | Mus musculus | N-([3,3'-bipyridin]-5-yl)-2,5-dimethoxybenzene-1-sulfonamide | |
0.000131 | - |
pH and temperature not specified in the publication | Mus musculus | 5-[[2-methoxy-5-(trifluoromethoxy)benzene-1-sulfonyl]amino]pyridine-3-carboxamide | |
0.000134 | - |
pH and temperature not specified in the publication | Mus musculus | 5-[(5-chloro-2-methoxybenzene-1-sulfonyl)amino]pyridine-3-carboxylic acid | |
0.000147 | - |
pH and temperature not specified in the publication | Mus musculus | 5-chloro-2-methoxy-N-[5-(4-methylphenyl)pyridin-3-yl]benzene-1-sulfonamide | |
0.00016 | - |
pH and temperature not specified in the publication | Mus musculus | 5-chloro-2-methoxy-N-[5-(3-methylphenyl)pyridin-3-yl]benzene-1-sulfonamide | |
0.000178 | - |
pH and temperature not specified in the publication | Mus musculus | 5-chloro-2-methoxy-N-[5-(2-methylphenyl)pyridin-3-yl]benzene-1-sulfonamide | |
0.000183 | - |
pH and temperature not specified in the publication | Mus musculus | 5-methyl-3-[3-[3-(trifluoromethyl)phenyl]prop-2-yn-1-yl]oxolan-2-one | |
0.000193 | - |
pH and temperature not specified in the publication | Mus musculus | 5-[(5-chloro-2-methoxybenzene-1-sulfonyl)amino]-N-ethylpyridine-3-carboxamide | |
0.000198 | - |
pH and temperature not specified in the publication | Mus musculus | 5-chloro-N-[5-(4-chlorophenyl)pyridin-3-yl]-2-methoxybenzene-1-sulfonamide | |
0.00031 | - |
pH and temperature not specified in the publication | Mus musculus | 5-[(5-chloro-2-methoxybenzene-1-sulfonyl)amino]-N-phenylpyridine-3-carboxamide | |
0.000322 | - |
pH and temperature not specified in the publication | Mus musculus | 2-cyano-6-methoxy-N-(pyridin-3-yl)benzene-1-sulfonamide | |
0.000432 | - |
pH and temperature not specified in the publication | Mus musculus | 5-[[5-chloro-2-(trifluoromethoxy)benzene-1-sulfonyl]amino]pyridine-3-carboxamide | |
0.000671 | - |
pH and temperature not specified in the publication | Mus musculus | 5-chloro-2-methoxy-N-[5-(4-methylpiperazine-1-carbonyl)pyridin-3-yl]benzene-1-sulfonamide | |
0.000876 | - |
pH and temperature not specified in the publication | Mus musculus | 3-methoxy-N-(pyridin-3-yl)[1,1'-biphenyl]-2-sulfonamide | |
0.000896 | - |
pH and temperature not specified in the publication | Mus musculus | 2-methoxy-5-methyl-N-(pyridin-3-yl)benzene-1-sulfonamide | |
0.00149 | - |
pH and temperature not specified in the publication | Mus musculus | 3-methoxy-2-[(pyridin-3-yl)sulfamoyl]benzamide | |
0.00151 | - |
pH and temperature not specified in the publication | Mus musculus | methyl 3-methoxy-2-[(pyridin-3-yl)sulfamoyl]benzoate | |
0.00417 | - |
pH and temperature not specified in the publication | Mus musculus | 5-chloro-2-methoxy-N-(pyridin-3-yl)benzene-1-sulfonamide | |
0.0103 | - |
pH and temperature not specified in the publication | Mus musculus | 2,5-dimethoxy-N-(pyridin-3-yl)benzene-1-sulfonamide |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is crucial for bone matrix mineralization | Mus musculus |