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Literature summary for 3.1.26.5 extracted from
- RNase P ribozymes selected in vitro to cleave a viral mRNA effectively inhibit its expression in cell culture (2000), J. Biol. Chem., 275, 10611-10622.
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | potential for using RNase P ribozymes as gene-targeting agents against any mRNA sequences, and using the selection procedure and a general approach for the engineering of RNase P ribozymes | Escherichia coli |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| G224A/G225A | ribozymes carrying the mutation at the catalytic RNA exhibit at least 10times higher cleavage efficiency than the wild-type enzyme | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pre-tRNA precursor + H2O | - |
Escherichia coli | tRNA + 5'-oligoribonucleotide | - |
? |  |
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