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Literature summary for 3.1.26.3 extracted from
- The endonuclease activity of RNase III is required for the regulation of antibiotic production by Streptomyces coelicolor (2008), Microbiology, 154, 3547-3555.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Streptomyces coelicolor |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| D70A | constructed point mutation, abolishes the catalytic activity of the protein but not its ability to bind to RNA substrates | Streptomyces coelicolor |
| additional information | rnc null mutant of Streptomyces coelicolor M145 does not produce actinorhodin or undecylprodigiosin. The strain bearing the disrupted rnc gene was designated JSE1880 | Streptomyces coelicolor |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Streptomyces coelicolor | globally regulates the production of antibiotics by Streptomyces coelicolor. Antibiotic production by wild-type and mutant strains of Streptomyces coelicolor analyzed | ? | - |
? |  |
| additional information | Streptomyces coelicolor M145 | globally regulates the production of antibiotics by Streptomyces coelicolor. Antibiotic production by wild-type and mutant strains of Streptomyces coelicolor analyzed | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptomyces coelicolor | Q9ZBQ7 | M145 | - |
| Streptomyces coelicolor M145 | Q9ZBQ7 | M145 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Streptomyces coelicolor |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | globally regulates the production of antibiotics by Streptomyces coelicolor. Antibiotic production by wild-type and mutant strains of Streptomyces coelicolor analyzed | Streptomyces coelicolor | ? | - |
? | |
| additional information | globally regulates the production of antibiotics by Streptomyces coelicolor. Antibiotic production by wild-type and mutant strains of Streptomyces coelicolor analyzed | Streptomyces coelicolor M145 | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| double strand-specific endoRNase | - |
Streptomyces coelicolor |
| RNase III | - |
Streptomyces coelicolor |
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