Cloned (Comment) | Organism |
---|---|
construction of transgenic lines by microinjection of a DNA vector encoding the enzyme and the green fluorescent protein | Caenorhabditis elegans |
Protein Variants | Comment | Organism |
---|---|---|
additional information | dcr-1 gene N-terminal deletion and null mutants show defective RNAi and are steril, overview | Caenorhabditis elegans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dsRNA + H2O | Caenorhabditis elegans | cleavage to short RNA pieces | ? | - |
? | |
additional information | Caenorhabditis elegans | enzyme is essential, and is involved in RNA interference, i.e. RNAi, a post-transcriptional gene-silencing phenomenon, and germ line development | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | - |
gene dcr-1 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dsRNA + H2O | cleavage to short RNA pieces | Caenorhabditis elegans | ? | - |
? | |
additional information | enzyme is essential, and is involved in RNA interference, i.e. RNAi, a post-transcriptional gene-silencing phenomenon, and germ line development | Caenorhabditis elegans | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DCR-1 | - |
Caenorhabditis elegans |
Dicer-1 | - |
Caenorhabditis elegans |
RNase III | - |
Caenorhabditis elegans |