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Literature summary for 3.1.26.3 extracted from

  • Robertson, H.D.; Webster, R.E.; Zinder, N.D.
    Purification and properties of ribonuclease III from Escherichia coli (1968), J. Biol. Chem., 243, 82-91.
    View publication on PubMed
Search for more literature for 3.1.26.3

Activating Compound

Activating Compound Comment Organism Structure
NH4+ required Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
ribosome
-
 Escherichia coli 5840
-

Metals/Ions

Metals/Ions Comment Organism Structure
K+
-
 Escherichia coli
Mg2+ required Escherichia coli
Mn2+ required Escherichia coli
Na+ required Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000 55000
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
double-stranded RNA + H2O Escherichia coli cleaves multimeric tRNA precursor at the spacer region, also involved in processing of precursor rRNA, hnRNA and early T7-mRNA. Also cleaves double-stranded DNA and single-stranded RNA 5'-phosphooligonucleotides
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
double-stranded RNA + H2O
-
 Escherichia coli 5'-phosphooligonucleotides
-
 ?
double-stranded RNA + H2O cleaves multimeric tRNA precursor at the spacer region, also involved in processing of precursor rRNA, hnRNA and early T7-mRNA. Also cleaves double-stranded DNA and single-stranded RNA Escherichia coli 5'-phosphooligonucleotides
-
 ?

pH Range

pH Minimum pH Maximum Comment Organism
7.6 9.75
-
 Escherichia coli