Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.26.13 extracted from

  • Waters, J.; ONeal, W.; White, K.; Wakeford, C.; Lansdon, E.; Harris, J.; Svarovskaia, E.; Miller, M.; Borroto-Esoda, K.
    Mutations in the thumb-connection and RNase H domain of HIV type-1 reverse transcriptase of antiretroviral treatment-experienced patients (2009), Antivir. Ther. (Lond. ), 14, 231-239.
    View publication on PubMed

Application

Application Comment Organism
medicine genotypical and statistical analyzes in HIV-1 reverse transcriptase from antiretroviral treatment-naive and antiretroviral treatment-experienced patients. Within the RNase H domain, change K451 is present in 11% of treatment-experienced patients, but not in treatment-naive patients Human immunodeficiency virus 1
medicine within the RNase domain, mutation K451R is present in viral isolates of 11% of antiviral treatment-experienced patients but remaining 100% conserved among treatment-naive patients Human immunodeficiency virus 1

Protein Variants

Protein Variants Comment Organism
K451R mutation present in viral isolates of 11% of antiviral treatment-experienced patients but remaining 100% conserved among treatment-naive patients Human immunodeficiency virus 1

Organism

Organism UniProt Comment Textmining
Human immunodeficiency virus 1
-
-
-