Literature summary for 3.1.26.12 extracted from

Zhou, L.; Zhao, M.; Wolf, R.Z.; Graham, D.E.; Georgiou, G.
Transcriptional regulation of the Escherichia coli gene rraB, encoding a protein inhibitor of RNase E (2009), J. Bacteriol., 191, 6665-6674.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	RraB binds to the C-terminal region of RNase E, thus affecting both the protein composition of the degradosome and the endonucleolytic activity of RNase E. The glmS852::Tn5 allele results in an approximately 50% lower intracellular concentration of uridine 5'-diphospho-N-acetyl-glucosamine and confers a 5fold increase in the level of rraB mRNA, thereby lowering the RNase E activity. Reduction in cellular concentration of uridine 5'-diphospho-N-acetyl-glucosamine by the glmS852::Tn5 allele mediating a 2fold increase in beta-galactosidase activity from a chromosomal fusion of the 5' untranslated region of the rne gene to lacZ, results in increased expression of RraB, which may modulate the action of RNase E	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
rne-lacZ transcript + H2O	-	Escherichia coli	?	-	?

Synonyms

Synonyms	Comment	Organism
RNase E	-	Escherichia coli

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Release 2023.1 (January 2023)